Diazepine






17 Article(s)
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1 7293228 Biotransformation of [14C]midazolam in the rat in vitro and in vivo. Xenobiotica 1981 Jun 1
2 8064797 Binding of 5H-dibenzo[b,e][1,4]diazepine and chiral 5H-dibenzo[a,d]cycloheptene analogues of clozapine to dopamine and serotonin receptors. J Med Chem 1994 Aug 19 1
3 11204747 Synthesis, 5-HT1A and 5-HT2A receptor affinity of new 1-phenylpiperazinylpropyl derivatives of purine-2,6- and pyrrolidine-2,5-diones. Farmaco 2000 Jun-Jul 2
4 12929367 Synthesis of 6H-pyrrolo[3',4':2,3][1,4]diazepino[6,7,1-hi]indole-8,10(7H,9H)-diones using 3-bromo-4-(indol-1-yl)maleimide scaffold. Org Biomol Chem 2003 Mar 7 1
5 14723961 Design, synthesis and structure-affinity relationships of aryloxyanilide derivatives as novel peripheral benzodiazepine receptor ligands. Bioorg Med Chem 2004 Jan 15 1
6 15745814 Synthesis and SAR of diazepine and thiazepine TACE and MMP inhibitors. Bioorg Med Chem Lett 2005 Mar 15 2
7 16797790 Synthesis of a new series of heterocyclic scaffolds for medicinal purposes. Eur J Med Chem 2006 Aug 1
8 21751782 Mechanism of inhibition of the GluA2 AMPA receptor channel opening: consequences of adding an N-3 methylcarbamoyl group to the diazepine ring of 2,3-benzodiazepine derivatives. Biochemistry 2011 Aug 23 1
9 22059113 Mechanism of Inhibition of the GluA2 AMPA Receptor Channel Opening: the Role of 4-Methyl versus 4-Carbonyl Group on the Diazepine Ring of 2,3-Benzodiazepine Derivatives. ACS Chem Neurosci 2011 May 12 1
10 23402301 Mechanism of inhibition of the GluA2 AMPA receptor channel opening by talampanel and its enantiomer: the stereochemistry of the 4-methyl group on the diazepine ring of 2,3-benzodiazepine derivatives. ACS Chem Neurosci 2013 Apr 17 2
11 25497965 Synthesis and biological evaluation of novel chiral diazepine derivatives as bombesin receptor subtype-3 (BRS-3) agonists incorporating an antedrug approach. Bioorg Med Chem 2015 Jan 1 2
12 25677667 Discovery of novel oxazepine and diazepine carboxamides as two new classes of heat shock protein 90 inhibitors. Bioorg Med Chem Lett 2015 Mar 15 1
13 26524625 Novel chiral-diazepines function as specific, selective receptor agonists with variable coupling and species variability in human, mouse and rat BRS-3 receptor cells. Peptides 2016 Jan 2
14 28462720 Homology Modeling Inspired Synthesis of 5-HT2A Receptor Inhibitors: A Diazepine Analogue of the Atypical Antipsychotic JL13. Cent Nerv Syst Agents Med Chem 2017 1
15 29679218 Targeting matrix metalloproteinases with novel diazepine substituted cinnamic acid derivatives: design, synthesis, in vitro and in silico studies. Chem Cent J 2018 Apr 20 2
16 35187417 Development of Inhaled GABA<sub>A</sub> Receptor Modulators to Improve Airway Function in Bronchoconstrictive Disorders. ACS Pharmacol Transl Sci 2022 Feb 11 1
17 35450359 Diminishing GSH-Adduct Formation of Tricyclic Diazepine-based Mutant IDH1 Inhibitors. ACS Med Chem Lett 2022 Apr 14 2