Droxidopa






90 Article(s)
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1 1449487 Activation of an adrenergic pro-drug through sequential stereoselective action of tandem target enzymes. Biochem Biophys Res Commun 1992 Nov 30 1
2 1817730 Effects of L-threo-DOPS, a noradrenaline precursor, on the long-term potentiation in the rat hippocampal mossy fiber-CA3 region. Brain Res 1991 Dec 20 4
3 2110272 Diuretic effects of L-threo-3,4-dihydroxyphenylserine (L-threo-DOPS) in anesthetized rats. Jpn J Pharmacol 1990 Mar 5
4 2119267 [The effect of L-threo-DOPS on P-300 in parkinsonism]. Rinsho Shinkeigaku 1990 May 3
5 2890807 Effect of unnatural noradrenaline precursor on sympathetic control and orthostatic hypotension in dopamine-beta-hydroxylase deficiency. Lancet 1987 Nov 21 1
6 3090204 Inhibition of monoamine oxidase by 3,4-dihydroxyphenylserine. J Neurochem 1986 Aug 2
7 3106991 Studies on the central action of L-threo-3,4-dihydroxyphenyl-serine (L-threo-DOPS) in FLA-63-treated mice. Pharmacol Biochem Behav 1987 Feb 3
8 3108598 Effect of L-threo-3,4-dihydroxyphenylserine(L-threo-DOPS) on brain and serum MHPG levels in mice: evidence for NE formation in CNS. Life Sci 1987 Jun 8 2
9 3138156 Effects of L-threo-dihydroxyphenylserine on spinal reflexes and decerebrate rigidity in rats. Gen Pharmacol 1988 3
10 3149290 d,l-threo-3,4-dihydroxyphenylserine restores sympathetic control and cures orthostatic hypotension in dopamine beta-hydroxylase deficiency. J Hypertens Suppl 1988 Dec 3
11 3585225 Possible role of dopamine and noradrenaline in the regulation of prolactin secretion from an ectopic anterior pituitary gland in female rats. J Endocrinol 1987 Apr 2
12 3613861 Stimulation of prolactin secretion by L-3,4-dihydroxyphenyl-serine (L-DOPS) via central norepinephrine in the rat. Life Sci 1987 Aug 24 7
13 3938472 L-threo-3, 4-dihydroxyphenylserine treatment of Parkinson's disease. J Med 1985 2
14 4091266 Simple purification of aromatic L-amino acid decarboxylase from human pheochromocytoma using high-performance liquid chromatography. Anal Biochem 1985 Nov 1 1
15 4359658 Antagonism by DL-threo-DOPS of the suppression of a conditioned avoidance response induced by a dopamine-beta-hydroxylase inhibitor. J Neural Transm 1973 1
16 6121849 Age-related changes in the chronotropic effect and the enzymic decarboxylation of L-threo-3,4-dihydroxphenylserine in the rat heart. J Pharm Pharmacol 1981 Dec 1
17 6431755 Improvement in freezing phenomenon of Parkinson's disease after DL-threo-3, 4-dihydroxyphenylserine. Acta Med Okayama 1984 Jun 1
18 6735152 Catecholamine involvement in the control of growth hormone secretion in the domestic fowl. Gen Comp Endocrinol 1984 Jun 2
19 7834959 [The effect of droxidopa on the monoamine metabolsim in the human brain]. Rinsho Shinkeigaku 1994 Oct 3
20 7834960 [Study on the metabolism of droxidopa in humans]. Rinsho Shinkeigaku 1994 Oct 5
21 7936090 Reduction of nerve growth factor receptor immunoreactivity in ischaemic gerbil hippocampal CA1 neurons after treatment with L-threo-3,4-dihydroxyphenylserine (DOPS). Neurol Res 1994 Jun 6
22 8023359 The protective effect of L-threo-3,4-dihydroxyphenylserine on ischemic hippocampal neuronal death in gerbils. Stroke 1994 Jul 11
23 8216760 Attenuation of haloperidol-induced catalepsy by noradrenaline and L-threo-DOPS. J Neural Transm Park Dis Dement Sect 1993 2
24 8414219 Regulation of nerve growth factor secretion in L-M cells by catechol derivatives. Neurosci Res 1993 Jun 2
25 8486891 Dopamine B hydroxylase deficiency responsible for severe dysautonomic orthostatic hypotension in an elderly patient. J Am Geriatr Soc 1993 May 1
26 8579767 A new metabolic pathway of L-threo-3,4-dihydroxyphenylserine, a precursor amino acid of norepinephrine, in the brain. Studies by in vivo microdialysis. J Neural Transm Park Dis Dement Sect 1994 1
27 8836986 The metabolism of L-DOPA and L-threo-3,4-dihydroxyphenylserine and their effects on monoamines in the human brain: analysis of the intraventricular fluid from parkinsonian patients. J Neurol Sci 1996 Jul 1
28 8902314 The effects of the noradrenaline precursor, L-threo-3,4-dihydroxyphenylserine, in children with orthostatic intolerance. Clin Auton Res 1996 Aug 1
29 8945750 Enhancement of mRNA expression of tissue-type plasminogen activator by L-threo-3,4-dihydroxyphenylserine in association with ocular dominance plasticity. Neurosci Lett 1996 Nov 8 3
30 9335575 Structural and kinetic description of cytochrome c unfolding induced by the interaction with lipid vesicles. Biochemistry 1997 Oct 21 1
31 9603211 Restoration of norepinephrine and reversal of phenotypes in mice lacking dopamine beta-hydroxylase. J Neurochem 1998 Jun 1
32 9804294 Suppression of hyperemia after brain ischemia by L-threo-3,4-dihydroxyphenylserine. Neuroreport 1998 Sep 14 1
33 10323317 L-threo-3,4-dihydroxyphenylserine enhances the orthostatic responses of plasma renin activity and angiotensin II in multiple system atrophy. J Neurol 1999 Mar 4
34 10594079 Norepinephrine-deficient mice have increased susceptibility to seizure-inducing stimuli. J Neurosci 1999 Dec 15 2
35 10821639 Tyrosine hydroxylase and aromatic L-amino acid decarboxylase do not coexist in neurons in the human anterior cingulate cortex. Neurosci Lett 1999 Jul 2 1
36 11054296 Direct evidence for the cooperative unfolding of cytochrome c in lipid membranes from H-(2)H exchange kinetics. J Mol Biol 2000 Nov 3 1
37 11454927 Use of dopamine-beta-hydroxylase-deficient mice to determine the role of norepinephrine in the mechanism of action of antidepressant drugs. J Pharmacol Exp Ther 2001 Aug 1
38 11479395 Amelioration of frozen gait by tandospirone, a serotonin 1A agonist, in a patient with pure akinesia developing resistance to L-threo-3,4-dihydroxyphenylserine. Clin Neuropharmacol 2001 Jul-Aug 1
39 11901210 Transport of amino acid-related compounds mediated by L-type amino acid transporter 1 (LAT1): insights into the mechanisms of substrate recognition. Mol Pharmacol 2002 Apr 1
40 12083775 Behavior of fluorinated analogs of L-(3,4-dihydroxyphenyl)alanine and L-threo-(3,4-dihydroxyphenyl)serine as substrates for Dopa decarboxylase. Biochem Biophys Res Commun 2002 Jul 5 1
41 12102462 The broader view: catecholamine abnormalities. Clin Auton Res 2002 May 2
42 15620318 On the effect of the solid support on the interleaflet distribution of lipids in supported lipid bilayers. Langmuir 2005 Jan 4 2
43 16212933 Fast, efficient reconstitution of the cyclooxygenases into proteoliposomes. Arch Biochem Biophys 2005 Nov 15 1
44 16463138 Interactions of Bax and tBid with lipid monolayers. J Membr Biol 2005 Sep 1
45 16899413 Noradrenaline is necessary for the hedonic properties of addictive drugs. Vascul Pharmacol 2006 Oct 2
46 17017570 The discovery of the pressor effect of DOPS and its blunting by decarboxylase inhibitors. J Neural Transm Suppl 2006 4
47 17214596 L-Dihydroxyphenylserine (L-DOPS): a norepinephrine prodrug. Cardiovasc Drug Rev 2006 Fall-Winter 3
48 17603032 The effects of various membrane physical-chemical properties on the aggregation kinetics of insulin. Chem Phys Lipids 2007 Sep-Oct 4
49 18368304 L-dihydroxyphenylserine (Droxidopa) in the treatment of orthostatic hypotension: the European experience. Clin Auton Res 2008 Mar 1
50 18665822 Measuring thrombin generation based sensitivity to activated protein C using an automated coagulometer (ACL 9000). Int J Lab Hematol 2008 Aug 1