alpha-naphthoflavone






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1 10606 Characterization and induction of aryl hydrocarbon (benzo(a)pyrene) hydroxylase in rabbit bone marrow. Res Commun Chem Pathol Pharmacol 1976 Oct 1
2 115598 Characteristics of aryl hydrocarbon hydroxylase activity in rat mammary epithlial cells grown in primary culture. Chem Biol Interact 1979 Oct 1
3 120463 Stimulation of microsomal drug oxidation activities by incorporation into microsomes of purified NADPH-cytochrome c (P-450) reductase. Jpn J Pharmacol 1979 Dec 1
4 153061 Increased aryl hydrocarbon hydroxylase activity in hepatic microsomes from streptozotocin-diabetic female rats. Xenobiotica 1978 Dec 1
5 170269 Regulation of aryl hydrocarbon (benzo-(A)-pyrene) hydroxylase activity in mammalian cells. Induction of hydroxylase activity by N6,O2'-dibutyryl8 adenosine 3':5'-monophosphate and aminophylline. J Biol Chem 1975 Oct 10 2
6 407010 The effects of benzoflavones on polycyclic hydrocarbon metabolism and skin tumor initiation. Chem Biol Interact 1977 Jun 1
7 550122 In vivo and in vitro inhibition of 3-methylcholanthrene-induced aryl hydrocarbon hydroxylase activity in rat liver by actinomycin D and 7,8-benzoflavone. Pol J Pharmacol Pharm 1979 Nov-Dec 2
8 912816 Effect of various chemicals on the metabolism of benzo(a)pyrene by cultured rat colon. Chem Biol Interact 1977 Sep 2
9 975055 Quantitative studies of the toxicity of benzo(a)pyrene to a mouse liver epithelial cell strain in culture. Cancer Res 1976 Nov 3
10 1159828 Alterations in microsomal metabolism of benzo[a]pyrene in mice fed butylated hydroxyanisole. J Natl Cancer Inst 1975 Aug 1
11 1192552 Inhibition of hepatic aryl hydrocarbon hydroxylase by 3-methylcholanthrene, 7,8-benzoflavone and other inducers added in vitro. Chem Biol Interact 1975 Nov 6
12 1269048 Studies on pulmonary aryl hydrocarbon hydroxylase activity in inbred strains of mice. Chem Biol Interact 1976 Jun 1
13 1306118 Caffeine as a probe for human cytochromes P450: validation using cDNA-expression, immunoinhibition and microsomal kinetic and inhibitor techniques. Pharmacogenetics 1992 Aug 1
14 1315629 The stability of dioxin-receptor ligands influences cytochrome P450IA1 expression in human keratinocytes. Carcinogenesis 1992 Apr 2
15 1329656 Mechanism of action of aryl hydrocarbon receptor antagonists: inhibition of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced CYP1A1 gene expression. Arch Biochem Biophys 1992 Nov 1 1
16 1455607 In vitro/in vivo effects of 7,8-benzoflavone on aryl hydrocarbon hydroxylase activity of mice. Vet Hum Toxicol 1992 Oct 10
17 1579548 Covalent binding of food carcinogens MeIQx, MeIQ and IQ to DNA and protein in microsomal incubations and isolated rat hepatocytes. Pharmacol Toxicol 1992 Mar 2
18 1643669 Inhibition of microsome-mediated binding of benzo[a]pyrene to DNA by flavonoids either in vitro or after dietary administration to rats. Chem Biol Interact 1992 Jun 15 1
19 1658599 Alpha-naphthoflavone acts as an antagonist of 2,3,7, 8-tetrachlorodibenzo-p-dioxin by forming an inactive complex with the Ah receptor. Mol Pharmacol 1991 Nov 3
20 1673402 Mouse hepatic microsomal enzyme that catalyzes oxidation of 11-oxo-delta 8-tetrahydrocannabinol to delta 8-tetrahydrocannabinol-11-oic acid. Drug Metab Dispos 1991 Jan-Feb 1
21 1690081 Characterization of a B cell helper factor(s) derived from CD5+ B cell hybridomas. Cell Immunol 1990 Apr 1 1
22 1720872 In vitro effects of L-ascorbic acid (vitamin C) on aryl hydrocarbon hydroxylase activity in hepatic microsomes of mice. Mutat Res 1991 Dec 1
23 1739422 Biochemical characterization of coumarin 7-hydroxylase activity in chick embryo liver microsomes. Biochem Pharmacol 1992 Jan 22 1
24 1806944 Cannabielsoin as a new metabolite of cannabidiol in mammals. Pharmacol Biochem Behav 1991 Nov 1
25 1988174 Roles of different cytochrome P450 enzymes in bioactivation of the potent hepatocarcinogen 3-methoxy-4-aminoazobenzene by rat and human liver microsomes. Carcinogenesis 1991 Jan 1
26 1997525 Metabolic effects of growth factors and polycyclic aromatic hydrocarbons on cultured human placental cells of early and late gestation. J Clin Endocrinol Metab 1991 Mar 1
27 2018552 Characteristics of cholesterol 7 alpha-hydroxylase and 7 alpha-hydroxycholesterol hydroxylase activities of rodent liver. Biochem Pharmacol 1991 May 15 1
28 2026586 Isolation and characterization of a cytochrome P-450 from rat kidney mitochondria that catalyzes the 24-hydroxylation of 25-hydroxyvitamin D3. J Biol Chem 1991 May 15 1
29 2059905 The characteristics of the microsomal hydroxylation of tolbutamide. Can J Physiol Pharmacol 1991 Mar 1
30 2113322 Aryl hydrocarbon hydroxylase activity levels in the hepatic microsomal fraction from MC- or TCDD-treated mice: a comparison between aromatic hydrocarbon responsive and non-responsive strains. Toxicol Lett 1990 Jun 3
31 2115161 In vitro effects of methylsulfonyl polychlorinated biphenyls and 7,8-benzoflavone on aryl hydrocarbon hydroxylase activity in human lymphoblastoid cells. Pharmacol Toxicol 1990 Apr 1
32 2155352 Effects of various inducers on diethylstilbestrol metabolism, drug-metabolizing enzyme activities and the aromatic hydrocarbon (Ah) receptor in male Syrian golden hamster liver. J Steroid Biochem 1990 Feb 1
33 2166479 The mechanism of action of alpha-naphthoflavone as an inhibitor of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced CYP1A1 gene expression. Arch Biochem Biophys 1990 Aug 15 1
34 2180560 Inactivation of 1,3-, 1,6-, and 1,8-dinitropyrene by cytochrome P-450 enzymes in human and rat liver microsomes. Cancer Res 1990 Apr 1 1
35 2241965 Constitutive and inducible expression of human cytochrome P450IA1 in yeast Saccharomyces cerevisiae: an alternative enzyme source for in vitro studies. Biochem Biophys Res Commun 1990 Oct 30 1
36 2359409 Involvement of cytochrome P-450c in alpha-naphthoflavone metabolism by rat liver microsomes. Mol Pharmacol 1990 Jun 5
37 2474030 Cytochrome P-450-dependent omega-oxidation of leukotriene B4 in rodent and human epidermis. J Invest Dermatol 1989 Aug 1
38 2493985 Peroxyl radical- and cytochrome P-450-dependent metabolic activation of (+)-7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene in mouse skin in vitro and in vivo. Cancer Res 1989 Apr 1 2
39 2501188 [Effects of 3-methylsulphonyl-4,5,3',4-tetrachlorobiphenyl and 7,8-benzoflavone on aryl hydrocarbon hydroxylase activity]. Fukuoka Igaku Zasshi 1989 May 1
40 2509067 Roles of individual human cytochrome P-450 enzymes in the bioactivation of benzo(a)pyrene, 7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene, and other dihydrodiol derivatives of polycyclic aromatic hydrocarbons. Cancer Res 1989 Nov 15 1
41 2547112 The cytotoxic effects of estradiol-17 beta, catecholestradiols and methoxyestradiols on dividing MCF-7 and HeLa cells. J Steroid Biochem 1989 Jun 1
42 2568025 Genotoxic effects of estrogens in epithelial cells from the neonatal mouse uterine cervix: modifications by metabolic modifiers. Teratog Carcinog Mutagen 1989 1
43 2573735 Induction of hepatic cytochrome P-450 and xenobiotic metabolizing enzymes in rats gavaged with an Alberta crude oil. J Toxicol Environ Health 1989 2
44 2703963 Biliary excretion of acetaminophen-glutathione as an index of toxic activation of acetaminophen: effect of chemicals that alter acetaminophen hepatotoxicity. J Pharmacol Exp Ther 1989 Mar 1
45 2811373 Involvement of cytochrome P-450 in the synthesis of 5,16,androstadien-3 beta-ol from pregnenolone in pig testes microsomes. J Steroid Biochem 1989 Oct 1
46 3037301 alpha-Naphthoflavone antagonism of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced murine lymphocyte ethoxyresorufin-O-deethylase activity and immunosuppression. Mol Pharmacol 1987 Jul 1
47 3079779 Aryl hydrocarbon hydroxylase activity in rat submandibular glands. J Dent Res 1986 Jan 1
48 3106806 A test using cultured cells with induced mixed-function oxygenase in the unscheduled DNA synthesis assay for detecting promutagens/procarcinogens. Mutat Res 1987 May 2
49 3110611 Investigations on DNA binding in rat liver and in Salmonella and on mutagenicity in the Ames test by emodin, a natural anthraquinone. Mutat Res 1987 Jul 1
50 3121205 Metabolic activation of a protein pyrolysate promutagen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline by rat liver microsomes and purified cytochrome P-450. Carcinogenesis 1988 Jan 1