remikiren






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1 1282588 Neurohormonal and blood pressure responses to low-dose infusion of an orally active renin inhibitor, Ro 42-5892, in salt-replete men. J Cardiovasc Pharmacol 1992 Dec 1
2 1502199 Species specificity of renin kinetics in transgenic rats harboring the human renin and angiotensinogen genes. Proc Natl Acad Sci U S A 1992 Aug 15 2
3 1720828 Effect of the renin response during renin inhibition: oral Ro 42-5892 in normal humans. J Cardiovasc Pharmacol 1991 Sep 1
4 1728438 Blood pressure control by the renin-angiotensin system in normotensive subjects. Assessment by angiotensin converting enzyme and renin inhibition. Circulation 1992 Jan 1
5 1830563 Ro 42-5892 is a potent orally active renin inhibitor in primates. Hypertension 1991 Jul 4
6 1873015 Nonparallel effects of renin inhibitor treatment on plasma renin activity and angiotensins I and II in hypertensive subjects. An assay-related artifact. Am J Hypertens 1991 Jul 1
7 1889841 Renin release regulation during acute renin inhibition in normal volunteers. Hypertension 1991 Sep 1
8 2203486 Prolonged blood pressure reduction by orally active renin inhibitor RO 42-5892 in essential hypertension. BMJ 1990 Jul 28 1
9 7586899 Clinical pharmacokinetics and efficacy of renin inhibitors. Clin Pharmacokinet 1995 Jul 1
10 7678159 Renin inhibitors as an example of presumptive irrelevant positive findings in the Salmonella/mammalian microsome assay (Ames test). Mutat Res 1993 Feb 1
11 7769797 Responses to an orally active renin inhibitor, remikiren (Ro 42-5892), after controlled salt depletion in humans. J Cardiovasc Pharmacol 1995 Mar 2
12 7795817 Determination of the renin inhibitor Ro 42-5892 in human plasma by automated pre-column derivatization, reversed-phase high-performance liquid chromatographic separation and electrochemical detection after post-column irradiation. J Chromatogr B Biomed Appl 1995 Mar 24 2
13 8206619 Vascular renin in the guinea pig. Suppression by the renin inhibitor remikiren. Hypertension 1994 Jun 1
14 8207739 Time dependency of the antihypertensive efficacy of the new renin inhibitor Ro 42-5892. J Hum Hypertens 1994 Feb 2
15 8222499 Efficacy and tolerability of the renin inhibitor Ro 42-5892 in patients with hypertension. Clin Pharmacol Ther 1993 Nov 1
16 8228207 Comparison of blood pressure and angiotensin responses to the renin inhibitor Ro 42-5892 and the angiotensin converting enzyme inhibitor enalapril in essential hypertension. J Hypertens 1993 Aug 4
17 8512659 Effects of an orally active renin inhibitor, Ro 42-5892, in patients with essential hypertension. Am J Hypertens 1993 May 2
18 8613199 Human renin-dependent hypertension in rats transgenic for human angiotensinogen. Hypertension 1996 Mar 3
19 8674188 Clinical validation of renin monoclonal antibody-based sandwich assays of renin and prorenin, and use of renin inhibitor to enhance prorenin immunoreactivity. Clin Chem 1996 Jul 1
20 8730920 Excretion and metabolism of remikiren, a potent orally active inhibitor of primate renin. Xenobiotica 1996 Mar 1
21 8730924 Pharmacokinetics of remikiren, a potent orally active inhibitor of human renin, in rat, dog and primates. Xenobiotica 1996 Mar 1
22 8783774 Remikiren (Ro 42-5892)--an orally active renin inhibitor in essential hypertension. Effects on blood pressure and the renin-angiotensin-aldosterone system. Am J Hypertens 1996 Jun 2
23 9095095 Dose effects of human renin in rats transgenic for human angiotensinogen. Hypertension 1997 Apr 2
24 9858773 Probing epitopes on human prorenin during its proteolytic and non-proteolytic activation. Biochim Biophys Acta 1998 Nov 10 2
25 12959271 Multiple dose pharmacokinetics and concentration effect relationship of the orally active renin inhibitor remikiren (Ro 42-5892) in hypertensive patients. Br J Clin Pharmacol 1993 Dec 2
26 26421414 Elucidation of the binding mechanism of renin using a wide array of computational techniques and biological assays. J Mol Graph Model 2015 Nov 1
27 30039962 Electrocatalytic Reduction of Nitrate Using Magnéli Phase TiO<sub>2</sub> Reactive Electrochemical Membranes Doped with Pd-Based Catalysts. Environ Sci Technol 2018 Aug 21 3
28 34514971 Interaction of the renin inhibitor aliskiren with the SARS-CoV-2 main protease: a molecular docking study. J Biomol Struct Dyn 2021 Sep 13 4