1,3,7-trimethyluric acid






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1 1306118 Caffeine as a probe for human cytochromes P450: validation using cDNA-expression, immunoinhibition and microsomal kinetic and inhibitor techniques. Pharmacogenetics 1992 Aug 1
2 8095225 Caffeine, estradiol, and progesterone interact with human CYP1A1 and CYP1A2. Evidence from cDNA-directed expression in Saccharomyces cerevisiae. Drug Metab Dispos 1993 Jan-Feb 2
3 9868741 Fluvoxamine is a potent inhibitor of the metabolism of caffeine in vitro. Pharmacol Toxicol 1998 Dec 2
4 10076532 Strain differences in CYP3A-mediated C-8 hydroxylation (1,3,7-trimethyluric acid formation) of caffeine in Wistar and Dark Agouti rats. Rapid metabolism of caffeine in debrisoquine poor metabolizer model rats. Biochem Pharmacol 1998 May 1 1
5 11985335 Effects of phenothiazine neuroleptics on the rate of caffeine demethylation and hydroxylation in the rat liver. Pol J Pharmacol 2001 Nov-Dec 1
6 12110375 Differences in caffeine and paraxanthine metabolism between human and murine CYP1A2. Biochem Pharmacol 2002 Jun 15 1
7 26967371 Role of Enzyme Flexibility in Ligand Access and Egress to Active Site: Bias-Exchange Metadynamics Study of 1,3,7-Trimethyluric Acid in Cytochrome P450 3A4. J Chem Theory Comput 2016 Apr 12 1
8 31123759 Identification of the caffeine to trimethyluric acid ratio as a dietary biomarker to characterise variability in cytochrome P450 3A activity. Eur J Clin Pharmacol 2019 Sep 1