1 | 611971 | [Effect of a diuretically-active pyrazolone derivative on renin activity, plasma angiotensin II and aldesterone concentration in healthy subjects]. | Verh Dtsch Ges Inn Med | 1977 Apr 17-21 |
2 |
2 | 2151433 | [The determination of specific IgE in allergy diagnosis. The clinical significance of specific IgE in drug allergies]. | Clin Ter | 1990 Dec 31 |
1 |
3 | 3489647 | [Immediate-type reactions to pyrazole derivatives: results of skin tests and antibody determinations]. | Dermatologica | 1986 |
1 |
4 | 3656349 | Cardiotonic agents. 6. Synthesis and inotropic activity of 2,4-dihydro-5-[4-(1H-imidazol-1-yl)phenyl]-3H-pyrazol-3-ones: ring-contracted analogues of imazodan (CI-914). | J Med Chem | 1987 Oct |
1 |
5 | 4472458 | Drug interactions. II. Binding of some pyrazolone and pyrazolidine derivatives to bovine serum albumin. | Chem Pharm Bull (Tokyo) | 1974 Jun |
1 |
6 | 12704373 | IgE-mediated immediate-type hypersensitivity to the pyrazolone drug propyphenazone. | J Allergy Clin Immunol | 2003 Apr |
1 |
7 | 14514315 | Rhenium(I)-induced cyclization of thiosemicarbazones derived from beta-keto esters. | Inorg Chem | 2003 Oct 6 |
1 |
8 | 15837310 | The development of monocyclic pyrazolone based cytokine synthesis inhibitors. | Bioorg Med Chem Lett | 2005 May 2 |
1 |
9 | 16043520 | Calcium-sensing soluble adenylyl cyclase mediates TNF signal transduction in human neutrophils. | J Exp Med | 2005 Aug 1 |
4 |
10 | 16460933 | Structure-guided identification of novel VEGFR-2 kinase inhibitors via solution phase parallel synthesis. | Bioorg Med Chem Lett | 2006 Apr 15 |
1 |
11 | 19914068 | Pyrazolone based TGFbetaR1 kinase inhibitors. | Bioorg Med Chem Lett | 2010 Jan 1 |
1 |
12 | 19926937 | The pyrazolone originally reported to be a formyl peptide receptor (FPR) 2/ALX-selective agonist is instead an FPR1 and FPR2/ALX dual agonist. | J Pharmacol Sci | 2009 Nov |
7 |
13 | 20534345 | Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor. | Chem Biol | 2010 May 28 |
1 |
14 | 21201166 | A second monoclinic polymorph of 4-(2-hydr-oxy-4-methoxy-benzyl-ideneamino)-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one. | Acta Crystallogr Sect E Struct Rep Online | 2008 Sep 20 |
1 |
15 | 22061645 | Pyrazolone-based anaplastic lymphoma kinase (ALK) inhibitors: control of selectivity by a benzyloxy group. | Bioorg Med Chem Lett | 2011 Dec 15 |
2 |
16 | 22154351 | Synthesis and biological evaluation of substituted pyrazoles as blockers of divalent metal transporter 1 (DMT1). | Bioorg Med Chem Lett | 2012 Jan 1 |
2 |
17 | 22320327 | Structure-based design of novel class II c-Met inhibitors: 2. SAR and kinase selectivity profiles of the pyrazolone series. | J Med Chem | 2012 Mar 8 |
3 |
18 | 22320343 | Structure-based design of novel class II c-Met inhibitors: 1. Identification of pyrazolone-based derivatives. | J Med Chem | 2012 Mar 8 |
1 |
19 | 23125802 | (Z)-3-Methyl-1-phenyl-4-[(p-tol-yl)(p-tolyl-amino)-methyl-idene]-1H-pyrazol-5(4H)-one. | Acta Crystallogr Sect E Struct Rep Online | 2012 Oct 1 |
1 |
20 | 23160941 | Functional characterization of three mouse formyl peptide receptors. | Mol Pharmacol | 2013 Feb |
1 |
21 | 23528231 | Characterization of a new mPGES-1 inhibitor in rat models of inflammation. | Prostaglandins Other Lipid Mediat | 2013 Apr-May |
1 |
22 | 24607578 | Development of novel pyrazolone derivatives as inhibitors of aldose reductase: an eco-friendly one-pot synthesis, experimental screening and in silico analysis. | Bioorg Chem | 2014 Apr |
2 |
23 | 24636540 | Synthesis and biologic evaluation of substituted 5-methyl-2-phenyl-1H-pyrazol-3(2H)-one derivatives as selective COX-2 inhibitors: molecular docking study. | Chem Biol Drug Des | 2014 Oct |
2 |
24 | 25173590 | Design, synthesis and pharmacological evaluation of 6,7-disubstituted-4-phenoxyquinoline derivatives as potential antitumor agents. | Bioorg Chem | 2014 Dec |
1 |
25 | 25182962 | Pyrazolone-quinazolone hybrids: a novel class of human 4-hydroxyphenylpyruvate dioxygenase inhibitors. | Bioorg Med Chem | 2014 Oct 1 |
2 |
26 | 25765567 | The TRPA1 channel mediates the analgesic action of dipyrone and pyrazolone derivatives. | Br J Pharmacol | 2015 Jul |
2 |
27 | 25977593 | Evaluation of pyrrolidine and pyrazolone derivatives as inhibitors of trypanosomal phosphodiesterase B1 (TbrPDEB1). | Tetrahedron Lett | 2015 May 20 |
1 |
28 | 26186011 | Tertiary Amine Pyrazolones and Their Salts as Inhibitors of Mutant Superoxide Dismutase 1-Dependent Protein Aggregation for the Treatment of Amyotrophic Lateral Sclerosis. | J Med Chem | 2015 Aug 13 |
1 |
29 | 26328495 | POMGNT1 Is Glycosylated by Mucin-Type O-Glycans. | Biol Pharm Bull | 2015 |
1 |
30 | 28411406 | Discovery of novel 2-substituted-4-(2-fluorophenoxy) pyridine derivatives possessing pyrazolone and triazole moieties as dual c-Met/VEGFR-2 receptor tyrosine kinase inhibitors. | Bioorg Chem | 2017 Jun |
4 |
31 | 29216268 | Docking and quantitative structure-activity relationship of bi-cyclic heteroaromatic pyridazinone and pyrazolone derivatives as phosphodiesterase 3A (PDE3A) inhibitors. | PLoS One | 2017 |
2 |
32 | 30653296 | NHC-Catalyzed Generation of α,β-Unsaturated Acylazoliums for the Enantioselective Synthesis of Heterocycles and Carbocycles. | Acc Chem Res | 2019 Feb 19 |
1 |
33 | 30990358 | Biological evaluation, molecular docking and DNA interaction studies of coordination compounds gleaned from a pyrazolone incorporated ligand. | Nucleosides Nucleotides Nucleic Acids | 2019 |
1 |
34 | 31498340 | Copper-catalyzed enantioselective alkynylation of pyrazole-4,5-diones with terminal alkynes. | Chem Commun (Camb) | 2019 Sep 24 |
1 |
35 | 31670091 | Potential use of edaravone to reduce specific side effects of chemo-, radio- and immuno-therapy of cancers. | Int Immunopharmacol | 2019 Dec |
1 |
36 | 31740202 | Design, synthesis, and evaluation of indeno[2,1-c]pyrazolones for use as inhibitors against hypoxia-inducible factor (HIF)-1 transcriptional activity. | Bioorg Med Chem | 2020 Jan 1 |
2 |
37 | 32031284 | Synthesis and biological evaluation of pyrazolone analogues as potential anti-inflammatory agents targeting cyclooxygenases and 5-lipoxygenase. | Arch Pharm (Weinheim) | 2020 Apr |
2 |
38 | 32841430 | Novel thiazole-pyrazolone hybrids as potent ACE inhibitors and their cardioprotective effect on isoproterenol-induced myocardial infarction. | Arch Pharm (Weinheim) | 2020 Dec |
3 |
39 | 33210922 | From Pyrazolones to Azaindoles: Evolution of Active-Site SHP2 Inhibitors Based on Scaffold Hopping and Bioisosteric Replacement. | J Med Chem | 2020 Dec 10 |
1 |
40 | 33705897 | A novel class of selective non-nucleoside inhibitors of human DNA methyltransferase 3A. | Bioorg Med Chem Lett | 2021 May 15 |
1 |
41 | 33945231 | Highly Diastereoselective Hydrosilane-Assisted Rhodium-Catalyzed Spiro-Type Cycloisomerization of Succinimide and Pyrazolone-Based Functional 1,6-Dienes. | Chem Asian J | 2021 Jul 5 |
1 |
42 | 33965840 | Discovery of pyrazolones as novel carboxylesterase 2 inhibitors that potently inhibit the adipogenesis in cells. | Bioorg Med Chem | 2021 Jun 15 |
6 |
43 | 33979735 | Structure-based modification of pyrazolone derivatives to inhibit mTORC1 by targeting the leucyl-tRNA synthetase-RagD interaction. | Bioorg Chem | 2021 Jul |
3 |
44 | 34007088 | Design and synthesis of pyrazolone-based compounds as potent blockers of SARS-CoV-2 viral entry into the host cells. | J Mol Struct | 2021 Oct 5 |
1 |
45 | 35429911 | Pyrazolones as inhibitors of immune checkpoint blocking the PD-1/PD-L1 interaction. | Eur J Med Chem | 2022 Jun 5 |
1 |