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2 | 2825613 | Studies on the mechanism of inhibition of chemotactic tripeptide stimulated human neutrophil polymorphonuclear leucocyte superoxide production by chloroquine and hydroxychloroquine. | Ann Rheum Dis | 1987 Oct |
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3 | 3019354 | Differential effects of mepacrine, chloroquine and hydroxychloroquine on superoxide anion generation, phospholipid methylation and arachidonic acid release by human blood monocytes. | Biochem Pharmacol | 1986 Sep 15 |
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4 | 3179169 | A dose-ranging study of the pharmacokinetics of hydroxy-chloroquine following intravenous administration to healthy volunteers. | Br J Clin Pharmacol | 1988 Sep |
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5 | 3500594 | Effect of antiinflammatory drugs on human interleukin-1-induced cartilage degradation. | Agents Actions | 1987 Aug |
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6 | 4853767 | Prevention of postoperative deep venous thrombosis in legs by orally administered hydroxychloroquine sulphate. | Br Med J | 1974 Jul 13 |
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7 | 6504946 | Modification of transoperative changes in blood fluidity by hydroxychloroquine: a possible explanation for the drug's antithrombotic effect. | Pharmatherapeutica | 1984 |
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8 | 7575694 | Tenidap in rheumatoid arthritis. A 24-week double-blind comparison with hydroxychloroquine-plus-piroxicam, and piroxicam alone. | Arthritis Rheum | 1995 Oct |
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9 | 8336306 | Selective regulation of cytokine secretion by hydroxychloroquine: inhibition of interleukin 1 alpha (IL-1-alpha) and IL-6 in human monocytes and T cells. | J Rheumatol | 1993 May |
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10 | 8485565 | The relevance of antimalarial therapy with regard to thrombosis, hypercholesterolemia and cytokines in SLE. | Lupus | 1993 Feb |
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11 | 8565026 | Hydroxychloroquine treatment of patients with human immunodeficiency virus type 1. | Clin Ther | 1995 Jul-Aug |
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12 | 8807116 | The effect of hydroxychloroquine on alloreactivity and its potential use for graft-versus-host disease. | Bone Marrow Transplant | 1996 Jun |
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13 | 9001825 | Inhibition of HIV-1 replication by hydroxychloroquine: mechanism of action and comparison with zidovudine. | Clin Ther | 1996 Nov-Dec |
7 |
14 | 9002011 | Chloroquine and hydroxychloroquine equally affect tumor necrosis factor-alpha, interleukin 6, and interferon-gamma production by peripheral blood mononuclear cells. | J Rheumatol | 1997 Jan |
6 |
15 | 9156650 | The lysosomotropic amines, chloroquine and hydroxychloroquine: a potentially novel therapy for graft-versus-host disease. | Leuk Lymphoma | 1997 Jan |
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16 | 9195122 | Prospective 6-month, double-blind trial of hydroxychloroquine treatment of CPDD. | Compr Ther | 1997 May |
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17 | 9352417 | The in vitro effect of hydroxychloroquine on skin morphology and transglutaminase. | Int J Dermatol | 1997 Sep |
2 |
18 | 9381529 | Immune suppression by lysosomotropic amines and cyclosporine on T-cell responses to minor and major histocompatibility antigens: does synergy exist? | Transplantation | 1997 Oct 15 |
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19 | 9385480 | Comparison of hydroxychloroquine with zidovudine in asymptomatic patients infected with human immunodeficiency virus type 1. | Clin Ther | 1997 Sep-Oct |
2 |
20 | 9416907 | Hydroxychloroquine reverses thrombogenic properties of antiphospholipid antibodies in mice. | Circulation | 1997 Dec 16 |
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21 | 9662754 | Alpha-interferon-induced arthritis: clinical presentation treatment, and prevention. | Semin Arthritis Rheum | 1998 Jun |
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22 | 9723661 | Hydroxychloroquine improves airflow and lowers circulating IgE levels in subjects with moderate symptomatic asthma. | J Allergy Clin Immunol | 1998 Aug |
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23 | 9779838 | Circulating levels of interleukin 10 and other cytokines in rheumatoid arthritis treated with cyclosporin A or combination therapy. | J Rheumatol | 1998 Oct |
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24 | 9918262 | Hypoglycemia induced by hydroxychloroquine in a type II diabetic treated for polyarthritis. | J Rheumatol | 1999 Jan |
2 |
25 | 10364906 | Hydroxychloroquine treatment for primary Sjögren's syndrome: its effect on salivary and serum inflammatory markers. | Ann Rheum Dis | 1999 Apr |
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26 | 10828029 | Hydroxychloroquine inhibits calcium signals in T cells: a new mechanism to explain its immunomodulatory properties. | Blood | 2000 Jun 1 |
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27 | 10848718 | Influence of hydroxychloroquine on the bioavailability of oral metoprolol. | Br J Clin Pharmacol | 2000 Jun |
2 |
28 | 11166661 | The anti-HIV-1 activity of chloroquine. | J Clin Virol | 2001 Feb |
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29 | 11167827 | Early induction of apoptosis in B-chronic lymphocytic leukaemia cells by hydroxychloroquine: activation of caspase-3 and no protection by survival factors. | Br J Haematol | 2001 Feb |
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30 | 11227493 | Caspase-3-dependent and caspase-3-independent pathways leading to chromatin DNA fragmentation in HL-60 cells. | Apoptosis | 2000 Feb |
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31 | 11359853 | Western and Chinese antirheumatic drug-induced T cell apoptotic DNA damage uses different caspase cascades and is independent of Fas/Fas ligand interaction. | J Immunol | 2001 Jun 1 |
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32 | 11384574 | Analysis of the ABCR (ABCA4) gene in 4-aminoquinoline retinopathy: is retinal toxicity by chloroquine and hydroxychloroquine related to Stargardt disease? | Am J Ophthalmol | 2001 Jun |
5 |
33 | 11440626 | Hydroxychloroquine enhances the endocrine secretion of adenovirus-directed growth hormone from rat submandibular glands in vivo. | Hum Gene Ther | 2001 Jul 1 |
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34 | 11849318 | Chloroquine decreases cell-surface expression of tumour necrosis factor receptors in human histiocytic U-937 cells. | Immunology | 2002 Jan |
1 |
35 | 12020529 | Hydroxychloroquine, hydroxycarbamide, and didanosine as economic treatment for HIV-1. | Lancet | 2002 May 11 |
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36 | 12148891 | Hydroxychloroquine-induced apoptosis of chronic lymphocytic leukemia involves activation of caspase-3 and modulation of Bcl-2/bax/ratio. | Leuk Lymphoma | 2002 May |
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37 | 12352275 | Controlled trial of hydroxychloroquine in schizophrenia. | J Clin Psychopharmacol | 2002 Oct |
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38 | 12813466 | Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine. | Oncogene | 2003 Jun 19 |
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39 | 14963695 | The effects of colchicine and hydroxychloroquine on the cyclo-oxygenases COX-1 and COX-2. | Rheumatol Int | 2005 Jun |
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40 | 14989426 | Effects of DMARDs on IL-1Ra levels in rheumatoid arthritis: is there any evidence? | Clin Exp Rheumatol | 2002 Sep-Oct |
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41 | 15507280 | Intracellular signaling triggered by antiphospholipid antibodies in platelets and endothelial cells: a pathway to targeted therapies. | Thromb Res | 2004 |
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42 | 15590764 | Hydroxychloroquine therapy in patients with primary Sjögren's syndrome may improve salivary gland hypofunction by inhibition of glandular cholinesterase. | Rheumatology (Oxford) | 2005 Apr |
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43 | 16130848 | Chronic inflammation of the peritoneum and vagina: review of its significance, immunologic pathogenesis, investigation and rationale for treatment. | J Reprod Med | 2005 Jul |
2 |
44 | 16142732 | RNA released from necrotic synovial fluid cells activates rheumatoid arthritis synovial fibroblasts via Toll-like receptor 3. | Arthritis Rheum | 2005 Sep |
1 |
45 | 16393772 | Aurothiomalate and hydroxychloroquine inhibit nitric oxide production in chondrocytes and in human osteoarthritic cartilage. | Scand J Rheumatol | 2005 Nov-Dec |
5 |
46 | 16722594 | Systemic lupus erythematosus. | Orphanet J Rare Dis | 2006 Mar 27 |
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47 | 16734620 | Hydroxychloroquine potentiates Fas-mediated apoptosis of rheumatoid synoviocytes. | Clin Exp Immunol | 2006 Jun |
3 |
48 | 16844666 | The transduction of rat submandibular glands by an adenoviral vector carrying the human growth hormone gene is associated with limited and reversible changes at the infusion site. | Toxicol Pathol | 2006 |
2 |
49 | 16964632 | Delayed hypersensitivity to hydroxychloroquine manifested by two different types of cutaneous eruptions in the same patient. | Allergol Immunopathol (Madr) | 2006 Jul-Aug |
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50 | 17574068 | Missing the bull's eye. | Surv Ophthalmol | 2007 Jul-Aug |
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