Hydroxychloroquine






518 Article(s)
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1 2110430 Hydroxychloroquine in decompensated, treatment-refractory noninsulin-dependent diabetes mellitus. A new job for an old drug? Ann Intern Med 1990 May 1 1
2 2825613 Studies on the mechanism of inhibition of chemotactic tripeptide stimulated human neutrophil polymorphonuclear leucocyte superoxide production by chloroquine and hydroxychloroquine. Ann Rheum Dis 1987 Oct 1
3 3019354 Differential effects of mepacrine, chloroquine and hydroxychloroquine on superoxide anion generation, phospholipid methylation and arachidonic acid release by human blood monocytes. Biochem Pharmacol 1986 Sep 15 1
4 3179169 A dose-ranging study of the pharmacokinetics of hydroxy-chloroquine following intravenous administration to healthy volunteers. Br J Clin Pharmacol 1988 Sep 2
5 3500594 Effect of antiinflammatory drugs on human interleukin-1-induced cartilage degradation. Agents Actions 1987 Aug 1
6 4853767 Prevention of postoperative deep venous thrombosis in legs by orally administered hydroxychloroquine sulphate. Br Med J 1974 Jul 13 1
7 6504946 Modification of transoperative changes in blood fluidity by hydroxychloroquine: a possible explanation for the drug's antithrombotic effect. Pharmatherapeutica 1984 1
8 7575694 Tenidap in rheumatoid arthritis. A 24-week double-blind comparison with hydroxychloroquine-plus-piroxicam, and piroxicam alone. Arthritis Rheum 1995 Oct 2
9 8336306 Selective regulation of cytokine secretion by hydroxychloroquine: inhibition of interleukin 1 alpha (IL-1-alpha) and IL-6 in human monocytes and T cells. J Rheumatol 1993 May 5
10 8485565 The relevance of antimalarial therapy with regard to thrombosis, hypercholesterolemia and cytokines in SLE. Lupus 1993 Feb 1
11 8565026 Hydroxychloroquine treatment of patients with human immunodeficiency virus type 1. Clin Ther 1995 Jul-Aug 1
12 8807116 The effect of hydroxychloroquine on alloreactivity and its potential use for graft-versus-host disease. Bone Marrow Transplant 1996 Jun 2
13 9001825 Inhibition of HIV-1 replication by hydroxychloroquine: mechanism of action and comparison with zidovudine. Clin Ther 1996 Nov-Dec 7
14 9002011 Chloroquine and hydroxychloroquine equally affect tumor necrosis factor-alpha, interleukin 6, and interferon-gamma production by peripheral blood mononuclear cells. J Rheumatol 1997 Jan 6
15 9156650 The lysosomotropic amines, chloroquine and hydroxychloroquine: a potentially novel therapy for graft-versus-host disease. Leuk Lymphoma 1997 Jan 1
16 9195122 Prospective 6-month, double-blind trial of hydroxychloroquine treatment of CPDD. Compr Ther 1997 May 1
17 9352417 The in vitro effect of hydroxychloroquine on skin morphology and transglutaminase. Int J Dermatol 1997 Sep 2
18 9381529 Immune suppression by lysosomotropic amines and cyclosporine on T-cell responses to minor and major histocompatibility antigens: does synergy exist? Transplantation 1997 Oct 15 1
19 9385480 Comparison of hydroxychloroquine with zidovudine in asymptomatic patients infected with human immunodeficiency virus type 1. Clin Ther 1997 Sep-Oct 2
20 9416907 Hydroxychloroquine reverses thrombogenic properties of antiphospholipid antibodies in mice. Circulation 1997 Dec 16 1
21 9662754 Alpha-interferon-induced arthritis: clinical presentation treatment, and prevention. Semin Arthritis Rheum 1998 Jun 1
22 9723661 Hydroxychloroquine improves airflow and lowers circulating IgE levels in subjects with moderate symptomatic asthma. J Allergy Clin Immunol 1998 Aug 1
23 9779838 Circulating levels of interleukin 10 and other cytokines in rheumatoid arthritis treated with cyclosporin A or combination therapy. J Rheumatol 1998 Oct 1
24 9918262 Hypoglycemia induced by hydroxychloroquine in a type II diabetic treated for polyarthritis. J Rheumatol 1999 Jan 2
25 10364906 Hydroxychloroquine treatment for primary Sjögren's syndrome: its effect on salivary and serum inflammatory markers. Ann Rheum Dis 1999 Apr 1
26 10828029 Hydroxychloroquine inhibits calcium signals in T cells: a new mechanism to explain its immunomodulatory properties. Blood 2000 Jun 1 1
27 10848718 Influence of hydroxychloroquine on the bioavailability of oral metoprolol. Br J Clin Pharmacol 2000 Jun 2
28 11166661 The anti-HIV-1 activity of chloroquine. J Clin Virol 2001 Feb 1
29 11167827 Early induction of apoptosis in B-chronic lymphocytic leukaemia cells by hydroxychloroquine: activation of caspase-3 and no protection by survival factors. Br J Haematol 2001 Feb 3
30 11227493 Caspase-3-dependent and caspase-3-independent pathways leading to chromatin DNA fragmentation in HL-60 cells. Apoptosis 2000 Feb 2
31 11359853 Western and Chinese antirheumatic drug-induced T cell apoptotic DNA damage uses different caspase cascades and is independent of Fas/Fas ligand interaction. J Immunol 2001 Jun 1 1
32 11384574 Analysis of the ABCR (ABCA4) gene in 4-aminoquinoline retinopathy: is retinal toxicity by chloroquine and hydroxychloroquine related to Stargardt disease? Am J Ophthalmol 2001 Jun 5
33 11440626 Hydroxychloroquine enhances the endocrine secretion of adenovirus-directed growth hormone from rat submandibular glands in vivo. Hum Gene Ther 2001 Jul 1 1
34 11849318 Chloroquine decreases cell-surface expression of tumour necrosis factor receptors in human histiocytic U-937 cells. Immunology 2002 Jan 1
35 12020529 Hydroxychloroquine, hydroxycarbamide, and didanosine as economic treatment for HIV-1. Lancet 2002 May 11 1
36 12148891 Hydroxychloroquine-induced apoptosis of chronic lymphocytic leukemia involves activation of caspase-3 and modulation of Bcl-2/bax/ratio. Leuk Lymphoma 2002 May 7
37 12352275 Controlled trial of hydroxychloroquine in schizophrenia. J Clin Psychopharmacol 2002 Oct 1
38 12813466 Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine. Oncogene 2003 Jun 19 4
39 14963695 The effects of colchicine and hydroxychloroquine on the cyclo-oxygenases COX-1 and COX-2. Rheumatol Int 2005 Jun 2
40 14989426 Effects of DMARDs on IL-1Ra levels in rheumatoid arthritis: is there any evidence? Clin Exp Rheumatol 2002 Sep-Oct 1
41 15507280 Intracellular signaling triggered by antiphospholipid antibodies in platelets and endothelial cells: a pathway to targeted therapies. Thromb Res 2004 1
42 15590764 Hydroxychloroquine therapy in patients with primary Sjögren's syndrome may improve salivary gland hypofunction by inhibition of glandular cholinesterase. Rheumatology (Oxford) 2005 Apr 6
43 16130848 Chronic inflammation of the peritoneum and vagina: review of its significance, immunologic pathogenesis, investigation and rationale for treatment. J Reprod Med 2005 Jul 2
44 16142732 RNA released from necrotic synovial fluid cells activates rheumatoid arthritis synovial fibroblasts via Toll-like receptor 3. Arthritis Rheum 2005 Sep 1
45 16393772 Aurothiomalate and hydroxychloroquine inhibit nitric oxide production in chondrocytes and in human osteoarthritic cartilage. Scand J Rheumatol 2005 Nov-Dec 5
46 16722594 Systemic lupus erythematosus. Orphanet J Rare Dis 2006 Mar 27 1
47 16734620 Hydroxychloroquine potentiates Fas-mediated apoptosis of rheumatoid synoviocytes. Clin Exp Immunol 2006 Jun 3
48 16844666 The transduction of rat submandibular glands by an adenoviral vector carrying the human growth hormone gene is associated with limited and reversible changes at the infusion site. Toxicol Pathol 2006 2
49 16964632 Delayed hypersensitivity to hydroxychloroquine manifested by two different types of cutaneous eruptions in the same patient. Allergol Immunopathol (Madr) 2006 Jul-Aug 1
50 17574068 Missing the bull's eye. Surv Ophthalmol 2007 Jul-Aug 1