Pub. Date : 1999 Feb 5
PMID : 9933169
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Induction of adenosine 3",5"-monophosphate (cAMP)-specific phosphodiesterase-7 (PDE7) was found to be a consequence of such costimulation. | Cyclic AMP | phosphodiesterase 7A | Homo sapiens |
| 2 | Induction of adenosine 3",5"-monophosphate (cAMP)-specific phosphodiesterase-7 (PDE7) was found to be a consequence of such costimulation. | Cyclic AMP | phosphodiesterase 7A | Homo sapiens |
| 3 | Increased PDE7 in T cells correlated with decreased cAMP, increased interleukin-2 expression, and increased proliferation. | Cyclic AMP | phosphodiesterase 7A | Homo sapiens |
| 4 | Selectively reducing PDE7 expression with a PDE7 antisense oligonucleotide inhibited T cell proliferation; inhibition was reversed by blocking the cAMP signaling pathways that operate through cAMP-dependent protein kinase (PKA). | Oligonucleotides | phosphodiesterase 7A | Homo sapiens |
| 5 | Selectively reducing PDE7 expression with a PDE7 antisense oligonucleotide inhibited T cell proliferation; inhibition was reversed by blocking the cAMP signaling pathways that operate through cAMP-dependent protein kinase (PKA). | Oligonucleotides | phosphodiesterase 7A | Homo sapiens |
| 6 | Selectively reducing PDE7 expression with a PDE7 antisense oligonucleotide inhibited T cell proliferation; inhibition was reversed by blocking the cAMP signaling pathways that operate through cAMP-dependent protein kinase (PKA). | Cyclic AMP | phosphodiesterase 7A | Homo sapiens |
| 7 | Selectively reducing PDE7 expression with a PDE7 antisense oligonucleotide inhibited T cell proliferation; inhibition was reversed by blocking the cAMP signaling pathways that operate through cAMP-dependent protein kinase (PKA). | Cyclic AMP | phosphodiesterase 7A | Homo sapiens |