Title : Cloning and characterization of the zebrafish (Danio rerio) aryl hydrocarbon receptor.

Pub. Date : 1999 Jan 18

PMID : 9931422






5 Functional Relationships(s)
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1 Treatment of zebrafish embryos and zebrafish liver cells with graded doses of TCDD results in a dose-dependent increase in zfAhR2 mRNA. Polychlorinated Dibenzodioxins aryl hydrocarbon receptor 2 Danio rerio
2 The time course for zfAhR2 and cytochrome P4501A mRNA induction by TCDD are similar. Polychlorinated Dibenzodioxins aryl hydrocarbon receptor 2 Danio rerio
3 In vitro produced zfAhR2 protein dimerizes with the rainbow trout aryl hydrocarbon receptor nuclear translocator (rtARNTb) and binds dioxin response elements derived from the rainbow trout CYP1A gene. Dioxins aryl hydrocarbon receptor 2 Danio rerio
4 Finally, transient coexpression of zfAhR2 and rtARNTb in COS-7 cells results in a TCDD dose-related increase in transcription driven by the rainbow trout CYP1A promoter and enhancer. carbonyl sulfide aryl hydrocarbon receptor 2 Danio rerio
5 Finally, transient coexpression of zfAhR2 and rtARNTb in COS-7 cells results in a TCDD dose-related increase in transcription driven by the rainbow trout CYP1A promoter and enhancer. Polychlorinated Dibenzodioxins aryl hydrocarbon receptor 2 Danio rerio