Title : Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer.

Pub. Date : 1999 Jan

PMID : 9916800






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 MeCP2 can mediate formation of transcriptionally repressive chromatin on methylated promoter templates in vitro, and this process can be reversed by trichostatin A (TSA), a specific inhibitor of histone deacetylase. trichostatin A methyl-CpG binding protein 2 Homo sapiens
2 MeCP2 can mediate formation of transcriptionally repressive chromatin on methylated promoter templates in vitro, and this process can be reversed by trichostatin A (TSA), a specific inhibitor of histone deacetylase. trichostatin A methyl-CpG binding protein 2 Homo sapiens