Title : Slow closed-state inactivation: a novel mechanism underlying ramp currents in cells expressing the hNE/PN1 sodium channel.

Pub. Date : 1998 Dec 1

PMID : 9822722






1 Functional Relationships(s)
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1 This conclusion is supported by data showing that divalent cations such as Cd2+ and Zn2+ (50-200 microM) slowed closed-state inactivation and also dramatically increased the ramp currents for DRG TTX-S currents and hNE channels but not for hSkM1 channels. Zinc sodium voltage-gated channel alpha subunit 4 Homo sapiens