Title : Coexpression of a multidrug-resistance gene (MDR1) and herpes simplex virus thymidine kinase gene as part of a bicistronic messenger RNA in a retrovirus vector allows selective killing of MDR1-transduced cells

Pub. Date : 1995 Apr

PMID : 9816003






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 More than 95% of the vincristine-resistant cells transfected or transduced with pHa-MDR-IRES-TK showed hypersensitivity to ganciclovir, which selects against cells expressing herpes simplex virus thymidine kinase. Vincristine lamin B receptor Homo sapiens
2 More than 95% of the vincristine-resistant cells transfected or transduced with pHa-MDR-IRES-TK showed hypersensitivity to ganciclovir, which selects against cells expressing herpes simplex virus thymidine kinase. Ganciclovir lamin B receptor Homo sapiens