Title : Activation of matrix-degrading metalloproteinases by mast cell proteases in atherosclerotic plaques.

Pub. Date : 1998 Nov

PMID : 9812908






1 Functional Relationships(s)
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1 Addition of the nonselective tryptase inhibitor antipain, the specific trypsinlike protease inhibitor 4-amidinophenylmethanesulfonyl fluoride, and the chymase inhibitor chymostatin reduced this increase in MMP activity by 30+/-6%, 23+/-6%, and 9+/-2%, respectively. (4-amidinophenyl)methanesulfonyl fluoride matrix metallopeptidase 1 Homo sapiens