Title : Solution studies of the antitumor complex dichloro 1,2-propylendiaminetetraacetate ruthenium (III) and of its interactions with proteins.

Pub. Date : 1998 Aug

PMID : 9755491






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 A mixed complex of ruthenium (III) with 1,2-propylendiaminetetraacetate (PDTA) and chloride--RAP hereafter--has been found to exhibit favorable anticancer properties in vivo. Ruthenium LDL receptor related protein associated protein 1 Homo sapiens
2 Under physiological conditions RAP slowly looses the two coordinated chlorine atoms to produce a number of ruthenium (III) reactive species; a description of the distribution of these species on the dependence of pH has been obtained through 1H NMR studies of the hyperfine shifted signals. Chlorine LDL receptor related protein associated protein 1 Homo sapiens
3 Under physiological conditions RAP slowly looses the two coordinated chlorine atoms to produce a number of ruthenium (III) reactive species; a description of the distribution of these species on the dependence of pH has been obtained through 1H NMR studies of the hyperfine shifted signals. ruthenium (iii) LDL receptor related protein associated protein 1 Homo sapiens
4 Under physiological conditions RAP slowly looses the two coordinated chlorine atoms to produce a number of ruthenium (III) reactive species; a description of the distribution of these species on the dependence of pH has been obtained through 1H NMR studies of the hyperfine shifted signals. Hydrogen LDL receptor related protein associated protein 1 Homo sapiens