Title : The alpha-chemokine, stromal cell-derived factor-1alpha, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways.

Pub. Date : 1998 Sep 4

PMID : 9722546






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 There was enhanced tyrosine phosphorylation and association of components of focal adhesion complexes such as the related adhesion focal tyrosine kinase, paxillin, and Crk. Tyrosine paxillin Homo sapiens
2 Wortmannin, a selective inhibitor of phosphatidylinositol 3-kinase, partially inhibited the SDF-1alpha-induced migration and tyrosine phosphorylation of paxillin. Wortmannin paxillin Homo sapiens
3 Wortmannin, a selective inhibitor of phosphatidylinositol 3-kinase, partially inhibited the SDF-1alpha-induced migration and tyrosine phosphorylation of paxillin. Tyrosine paxillin Homo sapiens