Title : Alcohol-mediated increases in acetaminophen hepatotoxicity: role of CYP2E and CYP3A.

Pub. Date : 1998 May 15

PMID : 9633991






1 Functional Relationships(s)
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1 In rats treated with ethanol or the combination of ethanol and isopentanol, the major higher chain alcohol in alcoholic beverages, TAO protects animals from increases in acetaminophen hepatotoxicity, suggesting a major role of CYP3A. isopentyl alcohol cytochrome P450, family 3, subfamily a, polypeptide 62 Rattus norvegicus