Title : Cardiac chronotropic mechanisms of dimethyl sulphoxide: inhibition of acetylcholinesterase and antagonism of negative chronotropy by atropine.

Pub. Date : 1976 May

PMID : 962427






4 Functional Relationships(s)
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1 DMSO produced concentration-dependent inhibition of acetylcholinesterase (AChE) activity of atrial homogenates. Dimethyl Sulfoxide ACE-1 Oryctolagus cuniculus
2 Cardiac chronotropic mechanisms of dimethyl sulphoxide: inhibition of acetylcholinesterase and antagonism of negative chronotropy by atropine. Dimethyl Sulfoxide ACE-1 Oryctolagus cuniculus
3 DMSO produced concentration-dependent inhibition of acetylcholinesterase (AChE) activity of atrial homogenates. Dimethyl Sulfoxide ACE-1 Oryctolagus cuniculus
4 The results indicate that the --C responses are due specifically to AChE inhibition by DMSO and resulting cholinergic influences on the atrial pacemaker. Dimethyl Sulfoxide ACE-1 Oryctolagus cuniculus