Pub. Date : 1998
PMID : 9619848
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Ginsenosides induce differential antinociception and inhibit substance P induced-nociceptive response in mice. | Ginsenosides | tachykinin 1 | Mus musculus |
| 2 | Interestingly, cotreatment of ginsenosides with SP also inhibited SP-induced pain behaviors (scratching, licking or biting of hind portion of body) with dose-dependent manner. | Ginsenosides | tachykinin 1 | Mus musculus |
| 3 | Interestingly, cotreatment of ginsenosides with SP also inhibited SP-induced pain behaviors (scratching, licking or biting of hind portion of body) with dose-dependent manner. | Ginsenosides | tachykinin 1 | Mus musculus |
| 4 | The ED50 for the inhibition of SP-induced pain behavior by ginsenosides was 30 (11-85, 95% C.I.) | Ginsenosides | tachykinin 1 | Mus musculus |
| 5 | These results suggest that ginsenosides have antinociceptive activity in formalin test and this effect is due to blocking of SP-induced nociceptive information to postsynaptic site(s) at the spinal level. | Ginsenosides | tachykinin 1 | Mus musculus |