Pub. Date : 1998 May 15
PMID : 9590268
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Paxillin is a cytoskeletally associated protein that is also tyrosine phosphorylated during PMN spreading and H2O2 release. | Tyrosine | paxillin | Homo sapiens |
2 | Paxillin is a cytoskeletally associated protein that is also tyrosine phosphorylated during PMN spreading and H2O2 release. | Hydrogen Peroxide | paxillin | Homo sapiens |
3 | Paxillin phosphorylation is kinetically slower than Syk phosphorylation and is inhibited with piceatannol, suggesting that paxillin is a substrate for Syk. | 3,3',4,5'-tetrahydroxystilbene | paxillin | Homo sapiens |
4 | Paxillin phosphorylation is kinetically slower than Syk phosphorylation and is inhibited with piceatannol, suggesting that paxillin is a substrate for Syk. | 3,3',4,5'-tetrahydroxystilbene | paxillin | Homo sapiens |
5 | These results indicate that PMN spreading and H2O2 release require a Syk-dependent signaling pathway leading to paxillin phosphorylation. | Hydrogen Peroxide | paxillin | Homo sapiens |