Pub. Date : 1997 Oct
PMID : 9475040
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Aluminium phosphide(AlP), a grain fumigant pesticide, was studied for its cardiotoxicity in anaesthetised rats. | aluminum phosphide | PDZ and LIM domain 3 | Rattus norvegicus |
| 2 | The cardiac glycogen, ATP and CP levels were significantly lowered in animals treated with 10, 20 and 40 mg of AlP. | Glycogen | PDZ and LIM domain 3 | Rattus norvegicus |
| 3 | The cardiac glycogen, ATP and CP levels were significantly lowered in animals treated with 10, 20 and 40 mg of AlP. | Adenosine Triphosphate | PDZ and LIM domain 3 | Rattus norvegicus |
| 4 | Thus it is suggested that the deleterious effect of AlP on heart is mediated by both declined cellular metabolism of the myocardium as well as by necrosis of the cardiac tissue resulting in the release of reactive oxygen intermediates. | Oxygen | PDZ and LIM domain 3 | Rattus norvegicus |