Title : Distinct time courses of increase in cytochromes P450 1A2, 2A5 and glutathione S-transferases during the progressive hepatitis associated with Helicobacter hepaticus.

Pub. Date : 1997 Nov

PMID : 9395219






4 Functional Relationships(s)
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1 The increase in CYP2A5 in mice aged over 12 months was confirmed by the observed increases in coumarin 7-hydroxylation (CYP2A5 substrate) in vitro and CYP2A5 mRNA levels by Northern blot analysis. coumarin cytochrome P450, family 2, subfamily a, polypeptide 5 Mus musculus
2 The increase in CYP2A5 in mice aged over 12 months was confirmed by the observed increases in coumarin 7-hydroxylation (CYP2A5 substrate) in vitro and CYP2A5 mRNA levels by Northern blot analysis. coumarin cytochrome P450, family 2, subfamily a, polypeptide 5 Mus musculus
3 The increase in CYP2A5 in mice aged over 12 months was confirmed by the observed increases in coumarin 7-hydroxylation (CYP2A5 substrate) in vitro and CYP2A5 mRNA levels by Northern blot analysis. coumarin cytochrome P450, family 2, subfamily a, polypeptide 5 Mus musculus
4 Perfusion of liver with nitroblue tetrazolium, an indicator for superoxide formation, demonstrated that in livers of infected mice, hepatocytes often co-expressed CYP2A5 and formazan deposition. Nitroblue Tetrazolium cytochrome P450, family 2, subfamily a, polypeptide 5 Mus musculus