Pub. Date : 1997 Oct 17
PMID : 9392525
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Calcium binding to recoverin: implications for secondary structure and membrane association. | Calcium | recoverin | Homo sapiens |
2 | Recoverin is an EF-hand calcium-binding protein reportedly involved in the transduction of light by vertebrate photoreceptor cells. | Calcium | recoverin | Homo sapiens |
3 | Measurements by circular dichroism presented here demonstrate that the binding of calcium to recoverin causes large structural changes. | Calcium | recoverin | Homo sapiens |
4 | Fluorescence measurements indicated that recoverin may aggregate or undergo structural changes independent of calcium binding as the calcium concentration is increased above 100 microM. | Calcium | recoverin | Homo sapiens |
5 | EGTA also appeared to affect the structure of recoverin independent of its chelation of calcium. | Egtazic Acid | recoverin | Homo sapiens |
6 | While calcium-induced conformational changes have been proposed to alter the membrane binding of recoverin through association of its myristoylated amino terminus, in the experiments presented here the partitioning of recoverin between the cytoplasmic and membrane compartments of the rod photoreceptor outer segment was unaffected by the concentration of calcium, therefore it appears unlikely that a calcium-myristoyl switch acts alone to anchor recoverin directly to the membrane. | Calcium | recoverin | Homo sapiens |