Title : 12-O-Tetradecanoylphorbol-13-acetate activates the Ras/extracellular signal-regulated kinase (ERK) signaling pathway upstream of SOS involving serine phosphorylation of Shc in NIH3T3 cells.

Pub. Date : 1997 Dec 5

PMID : 9388190






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Like growth factor-induced Shc phosphorylation, which leads to the association of Shc with Grb2, TPA also induced this association, but, correspondingly to the above results, the TPA-induced association was disrupted by in vitro treatment of the Shc immunoprecipitate with PP1. Tetradecanoylphorbol Acetate growth factor receptor bound protein 2 Mus musculus
2 Like growth factor-induced Shc phosphorylation, which leads to the association of Shc with Grb2, TPA also induced this association, but, correspondingly to the above results, the TPA-induced association was disrupted by in vitro treatment of the Shc immunoprecipitate with PP1. Tetradecanoylphorbol Acetate growth factor receptor bound protein 2 Mus musculus