Pub. Date : 1997 Sep
PMID : 9376223
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Maximally effective concentrations of the opioid agonist D-ala2-D-leu5-enkephalin resulted in some 2-3-fold enhancement of tyrosine phosphorylation of the p52 Shc adapter protein in a clone of Rat-1 fibroblasts transfected to express stably the murine delta opioid receptor. | Tyrosine | similar to Mitochondrial processing peptidase beta subunit, mitochondrial precursor (Beta-MPP; P-52) | Rattus norvegicus |
| 2 | Epidermal growth factor caused some 10-12-fold enhancement of tyrosine phosphorylation of p52 Shc and marked increases in the p46 and p66 forms. | Tyrosine | similar to Mitochondrial processing peptidase beta subunit, mitochondrial precursor (Beta-MPP; P-52) | Rattus norvegicus |
| 3 | Half-maximal effects of D-ala2-D-leu5-enkephalin on p52 Shc tyrosine phosphorylation were produced with sub-nanomolar concentrations, in agreement with previous results on the tyrosine phosphorylation of p44MAPK (Burt et al., 1996). | Tyrosine | similar to Mitochondrial processing peptidase beta subunit, mitochondrial precursor (Beta-MPP; P-52) | Rattus norvegicus |
| 4 | Half-maximal effects of D-ala2-D-leu5-enkephalin on p52 Shc tyrosine phosphorylation were produced with sub-nanomolar concentrations, in agreement with previous results on the tyrosine phosphorylation of p44MAPK (Burt et al., 1996). | Tyrosine | similar to Mitochondrial processing peptidase beta subunit, mitochondrial precursor (Beta-MPP; P-52) | Rattus norvegicus |
| 5 | p52 Shc became tyrosine phosphorylated more rapidly than p44MAPK in response to D-ala2-D-leu5-enkephalin and its enhanced tyrosine phosphorylation was maintained for at least 10 min. | Tyrosine | similar to Mitochondrial processing peptidase beta subunit, mitochondrial precursor (Beta-MPP; P-52) | Rattus norvegicus |
| 6 | p52 Shc became tyrosine phosphorylated more rapidly than p44MAPK in response to D-ala2-D-leu5-enkephalin and its enhanced tyrosine phosphorylation was maintained for at least 10 min. | Tyrosine | similar to Mitochondrial processing peptidase beta subunit, mitochondrial precursor (Beta-MPP; P-52) | Rattus norvegicus |