Title : Characterization of the AT1 angiotensin II receptor expressed in guinea pig liver.

Pub. Date : 1997 Jul

PMID : 9246947






7 Functional Relationships(s)
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1 The effect of 10 nM angiotensin II was blocked by the angiotensin II receptor AT1-selective antagonists irbesartan and losartan (Ki values of approximately 1 nM and approximately 10 nM for irbesartan and losartan respectively) but not by the AT2-selective antagonist PD123177. Irbesartan type-1 angiotensin II receptor Cavia porcellus
2 The effect of 10 nM angiotensin II was blocked by the angiotensin II receptor AT1-selective antagonists irbesartan and losartan (Ki values of approximately 1 nM and approximately 10 nM for irbesartan and losartan respectively) but not by the AT2-selective antagonist PD123177. Losartan type-1 angiotensin II receptor Cavia porcellus
3 The effect of 10 nM angiotensin II was blocked by the angiotensin II receptor AT1-selective antagonists irbesartan and losartan (Ki values of approximately 1 nM and approximately 10 nM for irbesartan and losartan respectively) but not by the AT2-selective antagonist PD123177. Irbesartan type-1 angiotensin II receptor Cavia porcellus
4 The effect of 10 nM angiotensin II was blocked by the angiotensin II receptor AT1-selective antagonists irbesartan and losartan (Ki values of approximately 1 nM and approximately 10 nM for irbesartan and losartan respectively) but not by the AT2-selective antagonist PD123177. Losartan type-1 angiotensin II receptor Cavia porcellus
5 The effect of 10 nM angiotensin II was blocked by the angiotensin II receptor AT1-selective antagonists irbesartan and losartan (Ki values of approximately 1 nM and approximately 10 nM for irbesartan and losartan respectively) but not by the AT2-selective antagonist PD123177. PD 123177 type-1 angiotensin II receptor Cavia porcellus
6 This effect of angiotensin II was completely blocked by the AT1-selective antagonists irbesartan and losartan, but only in a very limited fashion by PD123177. Irbesartan type-1 angiotensin II receptor Cavia porcellus
7 This effect of angiotensin II was completely blocked by the AT1-selective antagonists irbesartan and losartan, but only in a very limited fashion by PD123177. Losartan type-1 angiotensin II receptor Cavia porcellus