Pub. Date : 1997 Apr
PMID : 9150437
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Induction of O6-alkylguanine-DNA-alkyltransferase in the hepatocytes of rats following treatment with 2-acetylaminofluorene. | 2-Acetylaminofluorene | O-6-methylguanine-DNA methyltransferase | Rattus norvegicus |
| 2 | Molecular and immunohistological techniques have been used to study the induction in rat liver of the DNA repair protein O6-alkylguanine-DNA-alkyltransferase (ATase), following an acute dose (60 mg/kg) of the hepatocarcinogen, 2-acetylaminofluorene (2-AAF). | 2-Acetylaminofluorene | O-6-methylguanine-DNA methyltransferase | Rattus norvegicus |
| 3 | Molecular and immunohistological techniques have been used to study the induction in rat liver of the DNA repair protein O6-alkylguanine-DNA-alkyltransferase (ATase), following an acute dose (60 mg/kg) of the hepatocarcinogen, 2-acetylaminofluorene (2-AAF). | 2-Acetylaminofluorene | O-6-methylguanine-DNA methyltransferase | Rattus norvegicus |
| 4 | Molecular and immunohistological techniques have been used to study the induction in rat liver of the DNA repair protein O6-alkylguanine-DNA-alkyltransferase (ATase), following an acute dose (60 mg/kg) of the hepatocarcinogen, 2-acetylaminofluorene (2-AAF). | 2-Acetylaminofluorene | O-6-methylguanine-DNA methyltransferase | Rattus norvegicus |
| 5 | Molecular and immunohistological techniques have been used to study the induction in rat liver of the DNA repair protein O6-alkylguanine-DNA-alkyltransferase (ATase), following an acute dose (60 mg/kg) of the hepatocarcinogen, 2-acetylaminofluorene (2-AAF). | 2-Acetylaminofluorene | O-6-methylguanine-DNA methyltransferase | Rattus norvegicus |
| 6 | Thus, ATase induction in response to 2-AAF treatment was an hepatocyte-specific response and not confined to any particular region of the liver lobule. | 2-Acetylaminofluorene | O-6-methylguanine-DNA methyltransferase | Rattus norvegicus |