Pub. Date : 1996 Dec
PMID : 8997395
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In three different models of acute renal failure (ischemia, ureteral obstruction, and cisplatin administration), the p21WAF1/CIP1/SDI1 gene, the protein product of which is associated with cell-cycle interruption, terminal differentiation, and cellular senescence, was activated in murine kidney cells. | Cisplatin | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 2 | In three different models of acute renal failure (ischemia, ureteral obstruction, and cisplatin administration), the p21WAF1/CIP1/SDI1 gene, the protein product of which is associated with cell-cycle interruption, terminal differentiation, and cellular senescence, was activated in murine kidney cells. | Cisplatin | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 3 | We also present evidence that, in the cisplatin model, both p53-independent and p53-dependent induction of p21 mRNA occur simultaneously. | Cisplatin | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |