Title : Dual interaction of the malaria circumsporozoite protein with the low density lipoprotein receptor-related protein (LRP) and heparan sulfate proteoglycans.

Pub. Date : 1996 Nov 1

PMID : 8920859






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Blockage of LRP by RAP or anti-LRP antibodies on heparan sulfate-deficient CHO cells results in more than 90% inhibition of binding and endocytosis of recombinant CS protein. Heparitin Sulfate LDL receptor related protein associated protein 1 Homo sapiens
2 Blockage of LRP by RAP or anti-LRP antibodies on heparan sulfate-deficient CHO cells results in more than 90% inhibition of binding and endocytosis of recombinant CS protein. CAV protocol LDL receptor related protein associated protein 1 Homo sapiens
3 Heparinase-pretreatment of LRP-deficient fibroblasts or blockage of LRP on heparan sulfate-deficient CHO cells by RAP, lactoferrin, or anti-LRP antibodies reduces Plasmodium berghei invasion by 60-70%. Heparitin Sulfate LDL receptor related protein associated protein 1 Homo sapiens