Title : Characterization of acid extrusion mechanisms in cultured fetal rat hippocampal neurones.

Pub. Date : 1996 Jun 1

PMID : 8782109






1 Functional Relationships(s)
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1 In the absence of HCO3-, removal of external Na+ by substitution with N-methyl-D-glucamine caused a sustained intracellular acidification that was not observed when Na+ was replaced by Li+, but neither steady-state intracellular pH (pHi) nor the rate of pHi recovery from an imposed acid load were influenced by amiloride analogues or HOE 694, inhibitors of Na(+)-H+ exchange in other cell types. Meglumine glucose-6-phosphate isomerase Rattus norvegicus