Pub. Date : 1996 Apr
PMID : 8680546
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Duration of anti-cholecystokinin (CCK) action on the rat exocrine pancreas of new CCK receptor antagonist FK480 administered orally. | FR 120480 | cholecystokinin | Rattus norvegicus |
| 2 | Duration of anti-cholecystokinin (CCK) action on the rat exocrine pancreas of new CCK receptor antagonist FK480 administered orally. | FR 120480 | cholecystokinin | Rattus norvegicus |
| 3 | We assessed the duration of the anti-cholecystokinin (CCK) action of FK480, a new non-peptide CCK-A receptor antagonist developed in Japan, in an in vivo study in rats, comparing it with CR 1505. | FR 120480 | cholecystokinin | Rattus norvegicus |
| 4 | FK480 significantly inhibited both CCK-stimulated pancreatic juice volume flow and amylase output 0, 4, 8, and 12 h after oral administration, whereas the inhibitory effect of CR 1505 had completely disappeared by 8 h after oral administration. | FR 120480 | cholecystokinin | Rattus norvegicus |
| 5 | It was concluded that orally administered FK480 has a prolonged anti-CCK action. | FR 120480 | cholecystokinin | Rattus norvegicus |