Title : Recoverin in cultured human retinoblastoma cells: enhanced expression during morphological differentiation.

Pub. Date : 1996 Jul

PMID : 8666979






6 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Recoverin is a calcium-binding protein expressed in retinal photoreceptors. Calcium recoverin Homo sapiens
2 In Y79 cell monolayer cultures, recoverin was immunolocalized to the cell cytoplasm, and immunoreactivity was increased dramatically by the addition of 2 mM butyrate to the culture medium. Butyrates recoverin Homo sapiens
3 Addition of 4 mM dbcAMP resulted in a moderate increase in both recoverin immunoreactivity and number of cellular processes. Bucladesine recoverin Homo sapiens
4 Western and northern blots of butyrate and dbcAMP-treated Y79 cell cultures demonstrated an increase in recoverin protein and RNA expression, respectively, comparable with that observed with immunocytochemistry. Butyrates recoverin Homo sapiens
5 Western and northern blots of butyrate and dbcAMP-treated Y79 cell cultures demonstrated an increase in recoverin protein and RNA expression, respectively, comparable with that observed with immunocytochemistry. Bucladesine recoverin Homo sapiens
6 These data suggest that, under the influence of the differentiating agent butyrate, Y79 cells exhibit an increase in expression of the photoreceptor protein recoverin and a concomitant morphological differentiation toward a neuronal phenotype. Butyrates recoverin Homo sapiens