Title : Effects of dexamethasone and transforming growth factor-beta 2 on group II phospholipase A2 mRNA and activity levels in interleukin 1 beta- and forskolin-stimulated mesangial cells.

Pub. Date : 1996 Apr 15

PMID : 8615811






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The expression of 14 kDa group II phospholipase A2 [also referred to as secretory PLA2 (sPLA2)] is induced in rat glomerular mesangial cells by exposure to inflammatory cytokines and forskolin, a cAMP elevating agent. Colforsin phospholipase A2 group IIA Rattus norvegicus
2 The expression of 14 kDa group II phospholipase A2 [also referred to as secretory PLA2 (sPLA2)] is induced in rat glomerular mesangial cells by exposure to inflammatory cytokines and forskolin, a cAMP elevating agent. Cyclic AMP phospholipase A2 group IIA Rattus norvegicus
3 Previously we have shown that dexamethasone and transforming growth factor-beta 2 (TGF-beta 2) suppress sPLA2 protein synthesis and enzyme activity induced by cytokines and forskolin. Dexamethasone phospholipase A2 group IIA Rattus norvegicus
4 Previously we have shown that dexamethasone and transforming growth factor-beta 2 (TGF-beta 2) suppress sPLA2 protein synthesis and enzyme activity induced by cytokines and forskolin. Colforsin phospholipase A2 group IIA Rattus norvegicus
5 These data suggest that cytokine- and forskolin-induced sPLA2, expression is tightly controlled via both transcriptional and post-transcriptional mechanisms. Colforsin phospholipase A2 group IIA Rattus norvegicus