Pub. Date : 1995 Oct
PMID : 8570027
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The magnitude of functional in vivo 5-HT2A receptor blockade elicited by representative compounds from each of the six major structural classes of typical antipsychotics, and the representative atypical antipsychotics clozapine and risperidone, was indicated by their respective abilities to block the stimulus effects of the phenylalkylamine hallucinogen (-)DOM in the rat. | Risperidone | 5-hydroxytryptamine receptor 2A | Rattus norvegicus |
| 2 | In contrast, the atypical antipsychotics clozapine and risperidone elicit effective in vivo antagonism of 5-HT2A receptors without severe behavioral disruption. | Risperidone | 5-hydroxytryptamine receptor 2A | Rattus norvegicus |