Title : On the origin and fate of external acetylcholinesterase in peripheral nerve.

Pub. Date : 1978 Dec

PMID : 84869






4 Functional Relationships(s)
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Protein Name
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1 Although 217-AO readily inhibited AChE throughout the nerves, echothiophate spared significant amounts unless the tissues had first been homogenized. O,O-diethyl S-(2-dimethylaminoethyl) phosphorothioate ACE-1 Oryctolagus cuniculus
2 Notably, doses of echothiophate inhibiting 84% of the total AChE inhibited only 30% of the rapidly transported enzyme, suggesting that AChE was distributed between compartments differing greatly in their accessibility to this drug. Echothiophate ACE-1 Oryctolagus cuniculus
3 Notably, doses of echothiophate inhibiting 84% of the total AChE inhibited only 30% of the rapidly transported enzyme, suggesting that AChE was distributed between compartments differing greatly in their accessibility to this drug. Echothiophate ACE-1 Oryctolagus cuniculus
4 The quasi-irreversible inhibition of AChE by echothiophate was used to probe the dynamics of the external enzyme. Echothiophate ACE-1 Oryctolagus cuniculus