Title : Inhibitory effect of curcumin on 12-O-tetradecanoylphorbol-13-acetate-induced increase in ornithine decarboxylase mRNA in mouse epidermis.

Pub. Date : 1993 Feb

PMID : 8435870






4 Functional Relationships(s)
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1 Inhibitory effect of curcumin on 12-O-tetradecanoylphorbol-13-acetate-induced increase in ornithine decarboxylase mRNA in mouse epidermis. Curcumin ornithine decarboxylase, structural 1 Mus musculus
2 Topical administration of 1, 3 or 10 mumol curcumin together with 5 nmol TPA inhibited by 66, 81 and 91% respectively TPA-induced increases in epidermal ODC enzyme activity measured 5 h later. Curcumin ornithine decarboxylase, structural 1 Mus musculus
3 The results indicate that curcumin inhibits TPA-induced increases in epidermal ODC enzyme activity by inhibiting the synthesis and/or enhancing the breakdown of ODC mRNA. Curcumin ornithine decarboxylase, structural 1 Mus musculus
4 The results indicate that curcumin inhibits TPA-induced increases in epidermal ODC enzyme activity by inhibiting the synthesis and/or enhancing the breakdown of ODC mRNA. Curcumin ornithine decarboxylase, structural 1 Mus musculus