Title : Repair of O6-methylguanine in rat pancreatic beta-cells after exposure to N-methyl-N-nitrosourea.

Pub. Date : 1993 Aug

PMID : 8325451






1 Functional Relationships(s)
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1 Primary cultures of neonatal rat beta-cells were shown to contain very low levels of O6-methylguanine-DNA-methyltransferase activity, the predominant mechanism for repairing O6-methyldeoxyguanosine in mammalian cells. O(6)-methyl-2'-deoxyguanosine O-6-methylguanine-DNA methyltransferase Rattus norvegicus