Pub. Date : 1976 Oct 1
PMID : 824399
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Histaminase (EC-1.4.3.6), one of the two catabolic enzymes for histamine, is contained in human granulocytes. | Histamine | amine oxidase copper containing 1 | Homo sapiens |
| 2 | Opsonized zymosan or the calcium ionophore A-23187 induce a dose-dependent release of histaminase from human granulocytes in vitro. | Zymosan | amine oxidase copper containing 1 | Homo sapiens |
| 3 | Opsonized zymosan or the calcium ionophore A-23187 induce a dose-dependent release of histaminase from human granulocytes in vitro. | Calcium | amine oxidase copper containing 1 | Homo sapiens |
| 4 | Opsonized zymosan-induced histaminase release was maximal in the presence of both calcium and magnesium, whereas ionophore release was magnesium independent. | Zymosan | amine oxidase copper containing 1 | Homo sapiens |
| 5 | Opsonized zymosan-induced histaminase release was maximal in the presence of both calcium and magnesium, whereas ionophore release was magnesium independent. | Calcium | amine oxidase copper containing 1 | Homo sapiens |
| 6 | Opsonized zymosan-induced histaminase release was maximal in the presence of both calcium and magnesium, whereas ionophore release was magnesium independent. | Magnesium | amine oxidase copper containing 1 | Homo sapiens |
| 7 | The total cellular content of histaminase could be released by both opsonized zymosan and ionophore. | Zymosan | amine oxidase copper containing 1 | Homo sapiens |
| 8 | Zymosan- and ionophore-induced histaminase release was inhibited by agents that are presumed to interfere with cell metabolism and disrupt microtubules. | Zymosan | amine oxidase copper containing 1 | Homo sapiens |
| 9 | Human granulocytes therefore may modulate the effect of histamine by releasing histaminase at a site of inflammation. | Histamine | amine oxidase copper containing 1 | Homo sapiens |