Pub. Date : 1994 May 24
PMID : 8193137
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In the present study, we investigated the role of N- and O-glycosylation in intracellular transport and extracellular cleavage-secretion of rabbit testicular ACE. | Nitrogen | angiotensin-converting enzyme | Oryctolagus cuniculus |
2 | Our experiments demonstrated that newly synthesized ACE acquires both N- and O-linked sugars before its cleavage-secretion and complete blockage of glycosylation results in rapid intracellular turnover of underglycosylated ACE. | n- and o-linked sugars | angiotensin-converting enzyme | Oryctolagus cuniculus |
3 | However, ACE synthesized without N-linked complex sugars and O-linked sugars can undergo normal transport and cleavage-secretion, and the underglycosylated protein is enzymatically active. | Nitrogen | angiotensin-converting enzyme | Oryctolagus cuniculus |
4 | However, ACE synthesized without N-linked complex sugars and O-linked sugars can undergo normal transport and cleavage-secretion, and the underglycosylated protein is enzymatically active. | Sugars | angiotensin-converting enzyme | Oryctolagus cuniculus |
5 | However, ACE synthesized without N-linked complex sugars and O-linked sugars can undergo normal transport and cleavage-secretion, and the underglycosylated protein is enzymatically active. | o-linked sugars | angiotensin-converting enzyme | Oryctolagus cuniculus |