Pub. Date : 1994 May
PMID : 8182553
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The purpose of this study was to determine if isopentanol alone or in combination with ethanol increased CYP2B1/2, CYP2E or CYP3A in the livers of rats. | isopentyl alcohol | cytochrome P450, family 2, subfamily b, polypeptide 1 | Rattus norvegicus |
2 | The purpose of this study was to determine if isopentanol alone or in combination with ethanol increased CYP2B1/2, CYP2E or CYP3A in the livers of rats. | isopentyl alcohol | cytochrome P450, family 2, subfamily e, polypeptide 1 | Rattus norvegicus |
3 | The purpose of this study was to determine if isopentanol alone or in combination with ethanol increased CYP2B1/2, CYP2E or CYP3A in the livers of rats. | isopentyl alcohol | cytochrome P450, family 3, subfamily a, polypeptide 62 | Rattus norvegicus |
4 | Isopentanol alone caused small increases in CYP2B1/2 and CYP3A. | isopentyl alcohol | cytochrome P450, family 2, subfamily b, polypeptide 1 | Rattus norvegicus |
5 | Isopentanol alone caused small increases in CYP2B1/2 and CYP3A. | isopentyl alcohol | cytochrome P450, family 3, subfamily a, polypeptide 62 | Rattus norvegicus |
6 | These results confirm our previous findings in cultured hepatocytes that when isopentanol is combined with ethanol, there is a synergistic increase in CYP2B1/2. | isopentyl alcohol | cytochrome P450, family 2, subfamily b, polypeptide 1 | Rattus norvegicus |
7 | Increases in CYP2B1/2, CYP2E and CYP3A protein moieties by ethanol, and by ethanol in combination with isopentanol, were associated with increases in their mRNAs. | isopentyl alcohol | cytochrome P450, family 2, subfamily b, polypeptide 1 | Rattus norvegicus |