Title : Potent SHC tyrosine phosphorylation by epidermal growth factor at low receptor density or in the absence of receptor autophosphorylation sites.

Pub. Date : 1994 Aug

PMID : 8036006






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The EGF receptor mutant Dc214 is able to activate the ras guanine nucleotide exchanger and phosphorylate mitogen-activated protein kinase (MAPK), presumable as a result of complex formation between tyrosine phosphorylated SHC and GRB2. Tyrosine growth factor receptor bound protein 2 Mus musculus