Title : The glomerulosclerosis gene Mpv17 encodes a peroxisomal protein producing reactive oxygen species.

Pub. Date : 1994 Nov 1

PMID : 7957077






8 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The glomerulosclerosis gene Mpv17 encodes a peroxisomal protein producing reactive oxygen species. Reactive Oxygen Species MpV17 mitochondrial inner membrane protein Mus musculus
2 Loss of the Mpv17 protein does not impair peroxisome biogenesis but instead leads to a reduced ability to produce reactive oxygen species (ROS). Reactive Oxygen Species MpV17 mitochondrial inner membrane protein Mus musculus
3 Loss of the Mpv17 protein does not impair peroxisome biogenesis but instead leads to a reduced ability to produce reactive oxygen species (ROS). Reactive Oxygen Species MpV17 mitochondrial inner membrane protein Mus musculus
4 In turn, overproduction of the Mpv17 gene in transfected cells results in dramatically enhanced levels of intracellular ROS indicating a direct involvement of Mpv17 in ROS production. Reactive Oxygen Species MpV17 mitochondrial inner membrane protein Mus musculus
5 In turn, overproduction of the Mpv17 gene in transfected cells results in dramatically enhanced levels of intracellular ROS indicating a direct involvement of Mpv17 in ROS production. Reactive Oxygen Species MpV17 mitochondrial inner membrane protein Mus musculus
6 In turn, overproduction of the Mpv17 gene in transfected cells results in dramatically enhanced levels of intracellular ROS indicating a direct involvement of Mpv17 in ROS production. Reactive Oxygen Species MpV17 mitochondrial inner membrane protein Mus musculus
7 These data reveal a role for the Mpv17 protein in peroxisomal reactive oxygen metabolism and establish a novel link between peroxisomal ROS production and glomerulosclerosis. Oxygen MpV17 mitochondrial inner membrane protein Mus musculus
8 These data reveal a role for the Mpv17 protein in peroxisomal reactive oxygen metabolism and establish a novel link between peroxisomal ROS production and glomerulosclerosis. Reactive Oxygen Species MpV17 mitochondrial inner membrane protein Mus musculus