Pub. Date : 1994 Nov 1
PMID : 7957077
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The glomerulosclerosis gene Mpv17 encodes a peroxisomal protein producing reactive oxygen species. | Reactive Oxygen Species | MpV17 mitochondrial inner membrane protein | Mus musculus |
| 2 | Loss of the Mpv17 protein does not impair peroxisome biogenesis but instead leads to a reduced ability to produce reactive oxygen species (ROS). | Reactive Oxygen Species | MpV17 mitochondrial inner membrane protein | Mus musculus |
| 3 | Loss of the Mpv17 protein does not impair peroxisome biogenesis but instead leads to a reduced ability to produce reactive oxygen species (ROS). | Reactive Oxygen Species | MpV17 mitochondrial inner membrane protein | Mus musculus |
| 4 | In turn, overproduction of the Mpv17 gene in transfected cells results in dramatically enhanced levels of intracellular ROS indicating a direct involvement of Mpv17 in ROS production. | Reactive Oxygen Species | MpV17 mitochondrial inner membrane protein | Mus musculus |
| 5 | In turn, overproduction of the Mpv17 gene in transfected cells results in dramatically enhanced levels of intracellular ROS indicating a direct involvement of Mpv17 in ROS production. | Reactive Oxygen Species | MpV17 mitochondrial inner membrane protein | Mus musculus |
| 6 | In turn, overproduction of the Mpv17 gene in transfected cells results in dramatically enhanced levels of intracellular ROS indicating a direct involvement of Mpv17 in ROS production. | Reactive Oxygen Species | MpV17 mitochondrial inner membrane protein | Mus musculus |
| 7 | These data reveal a role for the Mpv17 protein in peroxisomal reactive oxygen metabolism and establish a novel link between peroxisomal ROS production and glomerulosclerosis. | Oxygen | MpV17 mitochondrial inner membrane protein | Mus musculus |
| 8 | These data reveal a role for the Mpv17 protein in peroxisomal reactive oxygen metabolism and establish a novel link between peroxisomal ROS production and glomerulosclerosis. | Reactive Oxygen Species | MpV17 mitochondrial inner membrane protein | Mus musculus |