Title : Competitive antagonism of serotonin (5-HT)2C and 5-HT2A receptor-mediated phosphoinositide (PI) turnover by clozapine in the rat: a comparison to other antipsychotics.

Pub. Date : 1994 Nov 7

PMID : 7898773






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 5-HT2A receptors: risperidone (9.07) > spiperone > chlorpromazine > clozapine > thioridazine = fluphenazine > haloperidol (6.03). Risperidone 5-hydroxytryptamine receptor 2A Rattus norvegicus
2 5-HT2C receptors: clozapine (7.19) > chlorpromazine > risperidone > thioridazine > fluphenazine > spiperone > haloperidol (< 4.00). Risperidone 5-hydroxytryptamine receptor 2C Rattus norvegicus