Title : Regulation by CD45 of the tyrosine phosphorylation of high affinity IgE receptor beta- and gamma-chains.

Pub. Date : 1995 Apr 1

PMID : 7897197






2 Functional Relationships(s)
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1 Here we demonstrate that CD45 is necessary for the initiation of calcium flux through the transfected Fc epsilon RI. Calcium Fc epsilon receptor Ia Homo sapiens
2 In contrast to the effect of phosphatase inhibitors, the tyrosine phosphorylation levels of beta and gamma after aggregation of Fc epsilon RI are surprisingly reduced, relative to wild-type Jurkat, in the CD45-deficient cells. Tyrosine Fc epsilon receptor Ia Homo sapiens