Title : Disassembly of Son-of-sevenless proteins from Grb2 during p21ras desensitization by insulin.

Pub. Date : 1995 Jan 27

PMID : 7829473






2 Functional Relationships(s)
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Protein Name
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1 Insulin receptor signaling acutely stimulates GTP loading of p21ras, apparently by mobilizing complexes of Grb2 and the guanine nucleotide exchangers Son-of-sevenless (Sos) 1 and 2 to associate with tyrosine-phosphorylated proteins in the plasma membrane. Guanosine Triphosphate growth factor receptor bound protein 2 Mus musculus
2 Insulin receptor signaling acutely stimulates GTP loading of p21ras, apparently by mobilizing complexes of Grb2 and the guanine nucleotide exchangers Son-of-sevenless (Sos) 1 and 2 to associate with tyrosine-phosphorylated proteins in the plasma membrane. Tyrosine growth factor receptor bound protein 2 Mus musculus