Title : Zidovudine treatment prolongs survival and decreases virus load in the central nervous system of rhesus macaques infected perinatally with simian immunodeficiency virus.

Pub. Date : 1995 Jul

PMID : 7797947






1 Functional Relationships(s)
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1 Zidovudine did not prevent infection but did significantly increase survival time, which was associated with lower serum p26 viral core antigen levels, a lower virus burden in the cerebrospinal fluid (CSF), and lower CSF quinolinic acid levels than in untreated monkeys. Zidovudine transmembrane p24 trafficking protein 3 Homo sapiens