Title : Identification of RANTES receptors on human monocytic cells: competition for binding and desensitization by homologous chemotactic cytokines.

Pub. Date : 1993 Mar 1

PMID : 7679707






1 Functional Relationships(s)
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1 Although MCAF and MIP-1 alpha competed for RANTES binding to monocytes with apparent lower affinity (with estimated Kd of 6 and 1.6, nM respectively) both of these cytokines effectively desensitized the calcium mobilization induced by RANTES. Calcium C-C motif chemokine ligand 2 Homo sapiens