Title : Role of E-cadherin in the response of tumor cell aggregates to lymphatic, venous and arterial flow: measurement of cell-cell adhesion strength.

Pub. Date : 1995 May

PMID : 7657723






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Defects in the expression or function of the calcium dependent cell-cell adhesion molecule E-cadherin are common in invasive, metastatic carcinomas. Calcium cadherin 1 Homo sapiens
2 Although E-cadherin negative tumor cells formed cell aggregates in the presence of calcium, these were significantly more likely than E-cadherin positive cell aggregates to disaggregate in response to low shear forces, such as those found in a lymphatic vessel or venule (< 3.5 dyn/cm2). Calcium cadherin 1 Homo sapiens