Pub. Date : 1995 Aug
PMID : 7648625
7 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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1 | Transforming growth factor beta 1-hyaluronic acid interaction. | Hyaluronic Acid | transforming growth factor beta 1 | Gallus gallus | ||
2 | Chick embryo skin fibroblasts release transforming growth factor beta 1 that is able to modulate glycosaminoglycan synthesis and secretion. | Glycosaminoglycans | transforming growth factor beta 1 | Gallus gallus | ||
3 | Untreated transforming growth factor beta 1 suppressed the proliferative response of thymocytes to interleukin-1, as did transforming growth factor beta 1 pre-incubated with sulphated glycosaminoglycans. | sulphated glycosaminoglycans | transforming growth factor beta 1 | Gallus gallus | ||
4 | By contrast, transforming growth factor beta 1 lost its inhibitory capacity when preincubated with high molecular weight hyaluronic acid. | Hyaluronic Acid | transforming growth factor beta 1 | Gallus gallus | ||
5 | Digestion of transforming growth factor beta 1-hyaluronic acid complex with hyaluronidase released active transforming growth factor beta 1. | Hyaluronic Acid | transforming growth factor beta 1 | Gallus gallus | ||
6 | Digestion of transforming growth factor beta 1-hyaluronic acid complex with hyaluronidase released active transforming growth factor beta 1. | Hyaluronic Acid | transforming growth factor beta 1 | Gallus gallus | ||
7 | These results suggest that hyaluronic acid interacts with transforming growth factor beta 1, thus protecting the factor from tryptic degradation and may be a means of concentrating growth factor activity. | Hyaluronic Acid | transforming growth factor beta 1 | Gallus gallus |