Pub. Date : 1995 May
PMID : 7630918
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effect of cytotoxic prostaglandin, delta 12-prostaglandin J2 on E-cadherin expression in transformed epidermal cells in culture. | Prostaglandins | cadherin 1 | Homo sapiens |
| 2 | Effect of cytotoxic prostaglandin, delta 12-prostaglandin J2 on E-cadherin expression in transformed epidermal cells in culture. | delta(12)-prostaglandin J(2) | cadherin 1 | Homo sapiens |
| 3 | To clarify the mechanism of the cytotoxicity of these PGs, we examined the effects of delta 12-PGJ2 on the function and expression of E-cadherin, which plays a major role in the maintenance of intercellular adhesion, in transformed human epidermal cells in culture (HSC-1). | Prostaglandins | cadherin 1 | Homo sapiens |
| 4 | To clarify the mechanism of the cytotoxicity of these PGs, we examined the effects of delta 12-PGJ2 on the function and expression of E-cadherin, which plays a major role in the maintenance of intercellular adhesion, in transformed human epidermal cells in culture (HSC-1). | delta(12)-prostaglandin J(2) | cadherin 1 | Homo sapiens |
| 5 | Immunoblot analysis using a monoclonal antibody specific to human E-cadherin revealed that a 12-h incubation with 5 micrograms/ml of delta 12-PGJ2 induced E-cadherin expression in HSC-1 cells. | 9-deoxy-delta-9-prostaglandin D2 | cadherin 1 | Homo sapiens |
| 6 | Immunoblot analysis using a monoclonal antibody specific to human E-cadherin revealed that a 12-h incubation with 5 micrograms/ml of delta 12-PGJ2 induced E-cadherin expression in HSC-1 cells. | 9-deoxy-delta-9-prostaglandin D2 | cadherin 1 | Homo sapiens |
| 7 | Following a 12-h incubation with 5 micrograms/ml of delta 12-PGJ2, E-cadherin was also detected in a uniform pattern along cell junctions, although cell morphology was changed by the presence of cytotoxic PGs. | delta(12)-prostaglandin J(2) | cadherin 1 | Homo sapiens |
| 8 | These results suggest that the cytotoxicity of cyclopentenone PGs is related, at least in part, to E-cadherin expression in transformed human epidermal cells. | cyclopentenone | cadherin 1 | Homo sapiens |
| 9 | These results suggest that the cytotoxicity of cyclopentenone PGs is related, at least in part, to E-cadherin expression in transformed human epidermal cells. | Prostaglandins | cadherin 1 | Homo sapiens |