Title : Induction of p53 and apoptosis by delta 12-PGJ2 in human hepatocarcinoma SK-HEP-1 cells.

Pub. Date : 1995 Jul 17

PMID : 7628635






1 Functional Relationships(s)
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1 Western analysis using anti-p53 or anti-WAF1 monoclonal antibodies demonstrated that these two protein levels were increased 3 h after delta 12-PGJ2 treatment, and accumulated for up to 12 h. The induction of p53 protein seemed to be dependent on the increase of p53 mRNA level, which was inhibited by CHX treatment. delta 12-pgj2 cyclin dependent kinase inhibitor 1A Homo sapiens